Burden of skin disease and associated socioeconomic status in Asia: A cross-sectional analysis from the Global Burden of Disease Study 1990-2017

Abstract

Introduction Skin diseases have a significant global impact on quality of life, mental health, and loss of income. The burden of dermatologic conditions and its relationship with socioeconomic status in Asia is currently not well understood. Methods We selected Global Burden of Disease Study datasets to analyze disability-adjusted life years (DALYs) in 50 Asian countries, including Central Asia, northern Asia, eastern Asia, western Asia, southeastern Asia, and southern Asia, between 1990 and 2017. We compared DALYs to the socioeconomic status using the sociodemographic index and gross domestic product per capita of a country. Statistical analysis was performed using Pearson's correlation. Results Some countries had higher or lower than expected age-standardized DALY rates of skin diseases. Asian countries, especially high-income countries, had a high burden of inflammatory dermatoses, including acne, alopecia areata, atopic dermatitis, contact dermatitis, decubitus ulcers, psoriasis, pruritus, and seborrheic dermatitis. The burden of infectious dermatoses was greater in low-income Asian countries. The burden of skin cancer in Asia was relatively low. Conclusion There is a high burden of skin disease, especially inflammatory conditions, in Asian countries, but the burden of individual dermatoses in Asia varies by country and socioeconomic status. DALYs can potentially serve as a purposeful measure for directing resources to improve the burden of skin disease in Asia.

The Effectiveness of Microneedling Therapy on The Severity of Acne Scars According to Goodman and Baron: A Systematic review and meta-analysis

“…49 The Pooja study (2020) modality of PRP therapy in acne scars when monotherapy is used (single therapy) is not recommended because the results are unsatisfactory. 50 Ibrahim's study (2017) combined therapy in the treatment of acne scars showed satisfactory results when PRP was used in combination with other modalities such as microneedling and CO2 laser. 51 Faghihi study (2016) acne scar therapy using a combination of PRP with CO2 laser, gave insignificant results, a synergistic effect with uncomfortable side effects and took longer.…”

“…[3][4][5][6] In 2010, East Asia, South Asia, and Western Europe were the regions with the highest prevalence of acne vulgaris in the world in the 15-19 year age group (men: 49%; women: 51%) almost the same. 7,8 The management of acne scars is carried out by several methods such as topical preparations, dermabrasion, laser, excision (punch and elevation), subcutaneous incision, chemical peeling, dermal graft, filler, and microneedling (automated and dermaroller). 1,2,[9][10][11] Grade assessment acne scar severity using the Goodman and Baron subjective method.…”

Medicinal plants used for dermatological disorders among the people of the kingdom of Saudi Arabia: A narrative review

“…According to research, dermatological illnesses account for 1.8 % of worldwide disease burden and are rated fourth among all diseases that impact humans. Skin illnesses impact at least one-third of the population at some point in their lives, and they affect people of all ages, from infants to the elderly, and from all cultures ( Urban et al, 2021 , Tizek et al, 2019 ). There is significant variation in the number of different dermatological diseases among various regional and socio-economical situations.…”

“…There is significant variation in the number of different dermatological diseases among various regional and socio-economical situations. Skin cancers like melanoma, for example, are more common in high-income nations like Central Europe, North America, and Australia ( Urban et al, 2021 ). Even though skin problems are common throughout Asia, few research on skin diseases has been quantitatively reported.…”

“…Acute dermatitis is more common in children. Saudi Arabia came in third among Asian nations regarding contact dermatitis ( Urban et al, 2021 , Alshamrani et al, 2019 ).…”