Burden of respiratory illnesses in pediatric intensive care unit and predictors of mortality: Experience from a low resource country

Divecha, Chhaya; Tullu, Milind S.; Chaudhary, Satish

doi:10.1002/ppul.24351

Cited by 22 publications

(22 citation statements)

References 33 publications

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“…From this study it was also stated that one third of patients did not receive complete immunization and were malnourished, so this situation could increase the severity of infection and increase mortality. 12 Length of stay in PICU is a marker of illness severity, resource utilization, and performance. International studies had described small PICU with long stay patients 1-7,5% of the total PICU population.…”

Section: Discussionmentioning

confidence: 99%

Case distribution and survival rate in Pediatric Intensive Care Unit (PICU) at Banjarmasin, Indonesia

Anam¹,

Putri²,

Ramadhani³

et al. 2022

PEDSCIJ

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Introduction: Epidemiological studies about case distribution and survival in PICU is important to do. Knowledge of these epidemiological studies can assist in decision-making to improve patient quality of care. So far there is no data about the case distribution and survival rate of the patients in the PICU in Banjarmasin, Indonesia. This study aims to provide an overview of case distribution and survival rates of patients treated at the PICU of Ulin Hospital Banjarmasin. Methods: A retrospective study was conducted at the PICU of Ulin Hospital Banjarmasin. Data was taken from patients’ records from January 2017 to December 2018. Results: A total of 202 patients were admitted to the PICU, males 109 and females 93. The mortality rate was 17% with a survival rate, 83% with a mean length of stay of 10 days. The most common patient diagnosis was pneumonia 23%, meningoencephalitis 10%, and dengue shock syndrome 6%. The system commonly involved was respiratory system 26%, central nervous system 17%, and infection 13%. The median length of stay for overall admission was 9 days with a mean of 10 days. The cardiovascular and respiratory systems tend to have lower survival rates, 78%, and 79% respectively. Conclusions: This study shows that respiratory, neurological, and infectious diseases are the most common diseases that cause children to be admitted to the PICU. The mortality rate in this study was 17% with a mean length of stay of 10 days. It is necessary to focus on medical facilities and interventions to reduce respiratory-related mortality.

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Section: Discussionmentioning

confidence: 99%

Case distribution and survival rate in Pediatric Intensive Care Unit (PICU) at Banjarmasin, Indonesia

Anam¹,

Putri²,

Ramadhani³

et al. 2022

PEDSCIJ

View full text Add to dashboard Cite

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“…ARF is a generic term that encompasses a heterogeneous spectrum of diseases (5). There are multiple causes and risk factors for its development, microbiological, anatomical, social, demographic, exposure, nutritional, and hospital etiologies have been described (14)(15)(16). Careful assessment of history, complete physical examination, and evaluation of laboratory parameters may clarify the diagnosis (6).…”

Section: Introductionmentioning

confidence: 99%

Incidence, etiology, sociodemographic and clinical characterization of acute respiratory failure in pediatric patients at a high-altitude city: A multicenter cohort study

Muñoz

Haddad²,

Beltran³

et al. 2022

Front. Pediatr.

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BackgroundAcute respiratory failure is a life-threatening medical condition, associated with a variety of conditions and risk factors, including acute respiratory diseases which are a frequent cause of pediatric morbidity and mortality worldwide. In Colombia, the literature related to ARF is scarce.ObjectiveTo determine the incidence, causes, and sociodemographic and clinical characteristics of ARF in three hospitals in Bogota, a high-altitude city located in Colombia, during the COVID-19 pandemic.MethodsA multicenter prospective cohort study called the FARA cohort was developed between April 2020 – December 2021. Patients older than one month and younger than 18 years with respiratory distress who developed ARF were included.Results685 patients with respiratory distress were recruited in 21 months. The incidence density of ARF was found to be 41.7 cases per 100 person-day CI 95%, (37.3–47.7). The median age was 4.5 years.. Most of the patients consulted during the first 72 h after the onset of symptoms. Upon admission, 67.2% were potentially unstable. The most frequent pathologies were asthma, bronchiolitis, pneumonia, and sepsis. At admission, 75.6% of the patients required different oxygen delivery systems, 29,5% a low-flow oxygen system, 36,8% a high-flow oxygen system, and 9,28% invasive mechanical ventilation. SARS-COV-2, respiratory syncytial virus, rhinovirus/enterovirus, and adenovirus were the most frequently isolated viral agents. The coinfection cases were scarce.ConclusionsThis multicenter study, the FARA cohort, developed at 2,600 meters above sea level, shows the first data on incidence, etiology, sociodemographic and clinical characterization in a pediatric population with ARF that also concurs with the COVID-19 pandemic. These results, not only have implications for public health but also contribute to the scientific and epidemiological literature on a disease developed at a high altitude.

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“…Respiratory disease is a predominantly observed problem in neonatal and pediatric intensive care units (ICUs) ( 1 ). It is challenging to explain the complex relationship between infection, lung immaturity, and ventilator-caused lung injury in ventilated patients.…”

Section: Introductionmentioning

confidence: 99%

The clinical application of flexible bronchoscopy in a neonatal intensive care unit

Shi

Zhang

et al. 2022

Front. Pediatr.

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ObjectiveFlexible bronchoscopy is widely used in infants and it plays a crucial role. The aim of this study was to investigate the value and clinical safety of flexible bronchoscopy in a neonatal intensive care unit.MethodsA retrospective analysis was performed on the clinical data of 116 neonates who underwent flexible bronchoscopy and the outcomes of 147 procedures. A correlation analysis was performed on the relationship between flexible bronchoscopy findings, microscopic indications, and clinical disease.ResultsThe 147 procedures performed were due to the following reasons: problems related to artificial airways, 58 cases (39.45%); upper respiratory problems, 60 cases (40.81%) (recurrent dyspnea, 23 cases; upper airway obstruction, 17 cases; recurrent stridor, 14 cases; and hoarseness, six cases), lower respiratory problems, 51 cases (34.69%) (persistent pneumonia, 21 cases; suspicious airway anatomical disease, 21 cases; recurrent atelectasis, eight cases; and pneumorrhagia, one case), feeding difficulty three cases (2.04%). The 147 endoscopic examinations were performed for the following reasons: pathological changes, 141 cases (95.92%); laryngomalacia, 78 cases (53.06%); mucosal inflammation/secretions, 64 cases (43.54%); vocal cord paralysis, 29 cases (19.72%); trachea/bronchus stenosis, 17 cases (11.56%) [five cases of congenital annular constriction of the trachea, seven cases of left main tracheal stenosis, one case of the right middle bronchial stenosis, two cases of tracheal compression, and two cases of congenital tracheal stenosis]; subglottic lesions, 15 cases (10.20%) [eight cases of subglottic granulation tissue, six cases of subglottic stenosis, one cases of subglottic hemangioma]; tracheomalacia, 14 cases (9.52%); laryngeal edema, five cases (3.40%); tracheoesophageal fistula, four cases (2.72%); rhinostenosis, three cases (2.04%); tracheal bronchus, three cases (2.04%); glossoptosis, two cases (1.36%); laryngeal cyst, two cases (1.36%); laryngeal cleft, two cases (1.36%); tongue base cysts, one case (0.68%); and pneumorrhagia, one case (0.68%). Complications were rare and mild.ConclusionFlexible bronchoscopy is safe and effective for diagnosing and differentiating neonatal respiratory disorders in neonatal intensive care units.

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Burden of respiratory illnesses in pediatric intensive care unit and predictors of mortality: Experience from a low resource country

Cited by 22 publications

References 33 publications

Case distribution and survival rate in Pediatric Intensive Care Unit (PICU) at Banjarmasin, Indonesia

Case distribution and survival rate in Pediatric Intensive Care Unit (PICU) at Banjarmasin, Indonesia

Incidence, etiology, sociodemographic and clinical characterization of acute respiratory failure in pediatric patients at a high-altitude city: A multicenter cohort study

The clinical application of flexible bronchoscopy in a neonatal intensive care unit

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