Burden of hypertension in China over the past decades: Systematic analysis of prevalence, treatment and control of hypertension

Wang, Yixuan; Peng, Xiaoxia; Nie, Xiaolu; Chen, Li; Weldon, Ryan; Zhang, Weili; Xiao, Dingquan; Cai, Jun

doi:10.1177/2047487315617105

Cited by 61 publications

(53 citation statements)

References 17 publications

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“…The prevalence of hypertension in China has been rising rapidly during the past two decades [14,15]. Pooled data from 178 studies between 1999 and 2014 revealed that the overall prevalence was 28.9% [16]. Using the same data of 50,171 participants, our previous results demonstrated that the prevalence was 31.2% among men and 28.0% among women based on the JNC-7 guideline [10].…”

Section: Discussionmentioning

confidence: 86%

Prevalence and treatment of hypertension in China: impacts of 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline

et al. 2018

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a b s t r a c tThe definition, recommended treatment thresholds and targets of hypertension have been updated in the recent 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults. However, the impacts of this guideline on Chinese population are currently unknown. In this study, we aim to provide updated data in China using criteria from the updated guideline. A multistage, stratified sampling method was used to obtain a representative sample of 50,171 adults aged 18 years and above. Hypertension was defined as an average systolic blood pressure !130 mm Hg, or an average diastolic blood pressure !80 mm Hg, or self-reported use of antihypertensive medications in past 2 weeks. The weighted prevalence of hypertension was 60.1% (95% confidence interval [CI] 59.3%-61.0%). The treatment rate and recommended treatment rate were 16.8% (95% CI 16.1%-17.6%) and 53.7% (95% CI 52.6%-54.9%), respectively; the gap was more prominent among men and participants from rural areas. Hence, the adoption of the 2017 ACC/AHA guideline will lead to a substantial increase in both prevalence and number of patients needing treatment in China. The applicability of this guideline should be carefully evaluated based on evidence from Chinese population.

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Section: Discussionmentioning

confidence: 86%

Prevalence and treatment of hypertension in China: impacts of 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline

et al. 2018

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“…Although population awareness and medical compliance for treating hypertension have improved with time, more effort is still needed to appropriately manage hypertension in underdeveloped countries . As an underdeveloped region of China, many residents in Jilin province suffer from poorly controlled hypertension due to unhealthy living habits (high dietary salt and fat intake, as well as high alcohol and cigarette consumption), lower health awareness, lack of medical compliance, and climate variability . Poorly controlled hypertension might be attributed to AAD development .…”

Section: Introductionmentioning

confidence: 99%

Poor management of hypertension is an important precipitating factor for the development of acute aortic dissection

Dong

Piao

et al. 2019

J of Clinical Hypertension

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Hypertension is considered a key risk factor for acute aortic dissection (AAD). However, there is limited evidence demonstrating if hypertension management affects AAD development. The objective of this study was to investigate the role of hypertension management in AAD development in a Chinese population. A total of 825 AAD patients and 3300 age‐ and sex‐matched controls were included. The authors analyzed data on demographics, chronic comorbidities, and hypertension management of all participants. Multiple logistic regression analysis was used to estimate the adjusted odds ratios (AOR) and 95% confidence intervals (95% CI) for the relationship between chronic comorbidities, as well as the management of hypertension and AAD risk. After adjusting for other related factors, multivariate logistic regression identified hypertension, chronic kidney disease, Marfan syndrome, history of cardiovascular surgery, and history of smoking as risk factors for AAD. Among the identified risk factors, hypertension was an important and controllable risk factor for AAD development. Thus, the authors further evaluated how hypertension management affects AAD development. A total of 848 controls and 585 AAD patients with hypertension were enrolled in this part of the study. Hypertensive patients with AAD had a longer history, higher stage, poorer medication compliance, and poor control rates of blood pressure, among which poor medication compliance (Irregular vs Regular P < 0.001; Never treated vs Regular P < 0.001) and uncontrolled hypertension (P < 0.001) significantly increased the risk of AAD development. In conclusion, uncontrolled hypertension and poor medication compliance are important precipitating and controllable factors for AAD development.

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“…Hypertension is an important risk factor for the occurrence of stroke and stroke death in China [18,19]. The prevalence of hypertension is estimated to be up to 28.9% [20]. Moreover, the prevalence of hypertension also exhibits a trend of being high in the north and low in the south.…”

Section: Discussionmentioning

confidence: 99%

Mortality of Stroke and Its Subtypes in China: Results from a Nationwide Population-Based Survey

Chen

Jiang

et al. 2017

Neuroepidemiology

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Background: In China, stroke is the leading cause of death and contributes to a heavy disease burden. However, a nationwide population-based survey of the mortality of stroke and its subtypes is lacking for this country. Methods: Data derived from the National Epidemiological Survey of Stroke in China, which was a multistage, stratified clustering sampling-designed, cross-sectional survey, were analyzed. Mortality rate analyses were performed for 476,156 participants ≥20 years old from September 1, 2012 to August 31, 2013. Results: Of the 476,156 participants in the investigated population, 364 died of ischemic stroke, 373 of hemorrhagic stroke, and 21 of stroke of undetermined pathological type. The age-standardized mortality rates per 100,000 person-years among those aged ≥20 years were 114.8 for total stroke, 56.5 for ischemic stroke, and 55.8 for hemorrhagic stroke. The age-standardized mortality rates of total stroke, ischemic stroke, and hemorrhagic stroke were all higher in rural areas than those in urban areas. The stroke mortality rate was higher in the northern regions than in the south. An estimated 1.12 million people aged ≥20 years in China died of stroke during the period from September 1, 2012 to August 31, 2013. Conclusions: The burden of stroke in China is still heavy. Greater attention should be paid to improve strategies for preventing stroke.

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Burden of hypertension in China over the past decades: Systematic analysis of prevalence, treatment and control of hypertension

Cited by 61 publications

References 17 publications

Prevalence and treatment of hypertension in China: impacts of 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline

Prevalence and treatment of hypertension in China: impacts of 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline

Poor management of hypertension is an important precipitating factor for the development of acute aortic dissection

Mortality of Stroke and Its Subtypes in China: Results from a Nationwide Population-Based Survey

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