Bullous skin reaction induced by omeprazole

Stenier, C.; Fiasse, René; Bourlond, J.; Horsmans, Yves; Bourlond, A

doi:10.1111/j.1365-2133.1995.tb02656.x

Cited by 9 publications

(3 citation statements)

References 9 publications

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“…Omeprazole has been described as a cause of fixed‐drug eruptions (6), anaphylactic reactions (7) exfoliative dermatitis (8–10), alopecia (11), pityriasis rosea‐like eruption (12), erythema nodosum (13), bullous skin reactions (14), oral candidiasis (15), dry‐mouth syndrome (16), urticaria and angioedema (17–19), and acute dissemminated epidermal necrosis (20). However, no case of allergic contact dermatitis has been reported before.…”

Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis due to lansoprazole, a proton pump inhibitor

Vilaplana¹,

Romaguera²

2001

Contact Dermatitis

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Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis due to lansoprazole, a proton pump inhibitor

Vilaplana¹,

Romaguera²

2001

Contact Dermatitis

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“…The role of omeprazole in in ducing urticaria has been documented by rechallenge in a single case report 127]. Recently, lupus erythematosus [28], pemphigoid exacerbation [29], toxic epidermal necrolysis [30] and a reversible toxic bullous reaction [31 ] have been associated with omeprazole. Lupus-like syndrome has also been reported in association with domperidone [32], No such reactions were reported to our system.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Reactions to Alimentary Tract Medications: Results of a Seven-Year Surveillance Program and Review of the Literature

Dermatologia¹

1996

Dermatology

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Background: No systematic review of skin reactions to alimentary tract medications is available in the literature. Objective: We reviewed the reactions to alimentary tract medications reported to the surveillance system of the Italian Group for Epidemiologic Research in Dermatology (GISED). Methods: Between January 1988 and December 1994, 202 dermatologists in Italy reported to the coordinating center of GISED all the adverse reactions they observed during prespecified 2-month monitoring periods. Reactions classified under ATC codes A02–A04, A06, A07 and A09 were used for this analysis. Results: Of 2,789 reactions, 48 were attributed to alimentary tract medications. Urticaria/angioedema and exanthemas accounted for about 70% of these reactions. Fixed eruptions and lichenoid dermatitis accounted for a large part of the remaining reactions. Antiulcers and antiemetics appeared remarkably safe. Conclusion: Our data are reassuring with regard to the cutaneous reaction profile of several drugs taken for diseases of the alimentary tract.

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“…There have been occasional case reports of other types of reactions to PPIs and these include acute generalized exanthematous pustulosis (to lansoprazole), and pityriasis rosea, erythema nodosum and acute disseminated epidermal necrosis (with omeprazole) 7 –12 . PPIs may cause potentially severe drug eruptions.…”

mentioning

confidence: 99%