Bullous lesion with central umbilication in leukemia

Bullous leukemia cutis: a rare clinical subtype

“…In myeloid leukemias such as AML, the immunophenotypic profile can be positive for CD43, CD33, CD34, and CD117 [2,5,12]. Bullous LC is an unusual variant of LC and therefore difficult to diagnose [6][7][8][9][10]. For example, a reported patient with CLL had her bullous LC misdiagnosed as facial cellulitis [7].…”

Bullous leukemia cutis in a patient with T-cell prolymphocytic leukemia

“…Bullae formation is speculated to result from lymphatic obstruction, vascular occlusion, extensive upper dermal edema, or injury at the dermoepidermal junction. 10 …”

A Case of Leukaemia Cutis Presenting as Generalized Erythematous Nodules

“…There is no specific treatment for LC; the treatment of the underlying leukaemia improves the skin lesions (5). Radiotherapy and whole-body electron-beam irradiation are also considered as alternative treatments for widespread or resistant skin involvement.…”

“…Radiotherapy and whole-body electron-beam irradiation are also considered as alternative treatments for widespread or resistant skin involvement. Leukaemia cutis indicates poor prognosis (3,5).…”