Bullous leukemia cutis in a patient with T-cell prolymphocytic leukemia

Siu, S.; Jiang, Qiujie; Alpdoğan, Önder; Gochoco, Ashley; Gong, Jerald Z.; Lee, Jason B.; Sahu, Joya

doi:10.1016/j.jdcr.2016.05.008

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Cited by 2 publications

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“…In myeloid leukemias such as AML, the immunophenotypic profile can be positive for CD43, CD33, CD34, and CD117 [2,5,12]. Bullous LC is an unusual variant of LC and therefore difficult to diagnose [6][7][8][9][10]. For example, a reported patient with CLL had her bullous LC misdiagnosed as facial cellulitis [7].…”

Section: Case Discussionmentioning

confidence: 99%

Bullous leukemia cutis: a rare clinical subtype

Sandre

Osmond²,

Ghazarian³

et al. 2019

Dermatology Online Journal

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Section: Case Discussionmentioning

confidence: 99%

Bullous leukemia cutis: a rare clinical subtype

Sandre

Osmond²,

Ghazarian³

et al. 2019

Dermatology Online Journal

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“…Classic clinical features of skin manifestations include erythematous nodules and papules on the legs, asymptomatic reddish patches over the chest and upper back, and exfoliative dermatitis covering the entire body. [3][4][5] Other common associated findings include lymphocytosis, lymphadenopathy, and splenomegaly. 2 Diagnosis requires a thorough assessment of clinical presentation, immunophenotypic profiles, and serologic and cytologic studies.…”

Section: Introductionmentioning

confidence: 99%

Cutaneous Presentation of T-Cell Prolymphocytic Leukemia Mimicking Dermatomyositis

Ingrasci

Díaz-Pérez²,

Verne³

et al. 2021

The American Journal of Dermatopathology

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T-cell prolymphocytic leukemia (TPLL) is a rare form of leukemia by T lymphocytes at a post-thymic intermediate stage of development with an a/b immunophenotype. Facial involvement is common in TPLL and displays significant heterogeneity of the lesions' description and location. TPLL also contains a wide array of histology findings, cell cytology, and molecular studies. Here, we describe a TPLL patient who presented with an ill-defined erythematous patch involving the right axilla progressing to the left axilla, upper back, and face that resembled dermatomyositis. The diagnosis of TPLL was established using flow cytometry of bone marrow and peripheral blood, and histopathology of the involved skin. Dermatologists should be aware of these unique features.

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Bullous leukemia cutis in a patient with T-cell prolymphocytic leukemia

Cited by 2 publications

References 8 publications

Bullous leukemia cutis: a rare clinical subtype

Bullous leukemia cutis: a rare clinical subtype

Cutaneous Presentation of T-Cell Prolymphocytic Leukemia Mimicking Dermatomyositis

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