Bullous hemorrhagic lichen sclerosus of the breast: a report of two cases and review of the literature

Painful and oozing bullous lesions in a 74‐year‐old woman

“…With passing time, telangiectasia, bullae, haemorrhage and follicular plugging can also be found 9 . Extragenital LSA resembles classical anogenital LSA 1 …”

“…The exact pathogenesis of LSA is still unknown, but multiple aetiologies are believed to exist 1,9 . Autoimmune and genetic influences are often mentioned 1,3,9 .…”

“…However, there is a high estimated number of unrecorded cases. Women are affected more frequently than men, with a ratio varying from 1:1 to 10:1 1 …”

“…8 The exact pathogenesis of LSA is still unknown, but multiple aetiologies are believed to exist. 1,9 Autoimmune and genetic influences are often mentioned. 1,3,9 An infectious aetiology has been proposed in bullous LSA, with some authors suggesting an unconfirmed correlation with Borrelia infection and/or hepatitis C. The plaques and bullae may be the result of trauma or lymphatic oedema.…”

“…Lichen sclerosus et atrophicus (LSA) is a rare condition mainly localised in the anogenital region, but it can also affect extragenital areas in up to 20% of all cases 1,2 . A special, uncommon and rarely described variant of LSA is bullous LSA, which can affect both the genital and extragenital areas 2,3 .…”