Bryophyllum Pinnatum: A Review on Medicinal Benefits and Potent Bioactive Molecules

Abstract

Background: Since the inception, people are using herbal extracts as natural remedies for treatment of various diseases. Bryophyllum pinnatum, also known as the air plant, is well recognized herb used in folk medicine. It is native to Madagascar and further planted in tropical and subtropical areas around the world. It is known for the profusion of miniature plantlets which arises from the margins of phylloclade. Objective: The aim of this review is to provide the till date information regarding local and traditional uses, pharmacological activities and different phytochemicals reported from leaves extracts of Bryophyllum pinnatum. Methods: This review article contains a detailed survey of literature about Bryophyllum pinnatum available in different online databases such as; PubMed, Web of Science, Science Direct, Elsevier, and Google Scholar etc. upto 30 September 2018. In this review authors have focused on ethnopharmacological importance and phytochemicals present in Bryophyllum pinnatum and their structure. Structures of the phytochemical were prepared by ChemDraw tool. Results: This plant is used as traditional herbal medicine in around the globe due to medicinal properties like; anthelmintic, immunosuppressive, hepatoprotective, antinociceptive, anti-inflammatory, antidiabetic, nephroprotective, antioxidant, antimicrobial, analgesic, anticonvulsant and antipyretic. Phytochemical analysis of revealed the presence of many bioactive compounds like; alkaloids, flavonoids, triterpenes, steroids, glycosides, bufadienolides, lipids and organic acids etc. which are associated with different medicinal properties. Conclusion: Brophyllum pinnatum possess diversity of pharmacological importance and remarkable medicinal properties. Investigators have reported large number of phytochemicals exhibiting different medicinal properties of this herb but still correlation of medicinal properties.

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