Bruxism- is botulinum toxin an effective treatment?

Abstract

Data sourcesPubMed, Scopus, Web of Science, Embase, Cochrane, Scielo and Lilacs databases were searched from 1980 to March 2016. Literature reviews were explored in order to retrieve any other relevant papers.Study selectionRandomised controlled studies (RCTs), prospective and before and after studies that applied botulinum toxin (BoNT-A) to the masseter and/or temporalis muscles assessing objective and subjective parameters of bruxism published in English were included.Data extraction and synthesisThree reviewers independently assessed for eligibility. Disagreement was solved by discussion and when reaching consensus between at least two. Standard data items were extracted. Quality assessment was assessed using the Cochrane Collaboration's risk of bias tool and the Critical Appraisal Skills Program (CASP) tool. Before-After Study Checklist was used for the nonrandomised studies. Results were presented as a narrative review.ResultsFive studies were included in the review, of those three were RCTs and two before and after. A total of 188 subjects were included. Regimen was unique in each study and the follow-up ranged from two to 24 weeks. The risk of bias of the RCTs was assessed as low to unclear, while the before and after studies were assessed as of moderate risk of bias.ConclusionsThe authors concluded that botulinum toxin represents a possible option for the management of sleep bruxism (SB), minimising symptoms and reducing the intensity of contractions rather than for SB itself.

Reabilitação estética e funcional das bordas incisais dos dentes anteriores com fechamento de diastemas e reanatomização em resina composta: relato de caso clínico

“…Dentre diferentes abordagens terapêuticas para o bruxismo, podem ser usados dispositivos miorrelaxante em acrílico que irão proteger os dentes do desgaste 41 ; aplicação de toxina botulínica para reduzir a hiperatividade muscular [43][44][45][46] ; técnicas de biofeedback como terapia cognitivo comportamental visando a regulação da atividade excessiva do músculo 47,48 ; e até mesmo lançar mão do uso de aplicativos que ajudam o paciente a lembrar de desencostar os dentes 49 .…”

Fractures of implant fixtures: a retrospective clinical study

“…If deemed necessary, it may be a good idea to do perform a thorough sleep bruxism examination. If the test indicates that sleep bruxism is present, a stabilization splint, or botulinum toxin injection may be necessary as a preventive measure to reduce the occurrence of complications by lowering the symptoms of sleep bruxism and excessive bite force applied to the teeth [10][11][12][13][14].…”

Evaluation of Botulinum Toxin Effectiveness on Bruxism

“…Kumar ve ark. da çalışmalarında bruksim için BT-A masseter kası kontraksiyonlarını azaltarak şikayetleri minimalize eden optimal bir tedavi seçeneği olduğunu belirtmişlerdir (16). Bununla birlikte temporomandibuler eklem bozukluğu olanlarda veya tek taraflı çiğneme alışkanlığı olan hastalarda kas diğer tarafa göre daha kuvvetli olabileceği için ek doz gerekebilir.…”