Brown Recluse Spider Bite to the Face

Loxosceles Reclusa Bite to the Eyelid

“…Moreover, the potential causes of dermonecrotic lesions are extensive and include bacterial or fungal infection, viruses, drug reactions, pyoderma gangrenosum, other arthropod bites, focal vasculitis, thromboembolic phenomena, Lyme disease, neoplasms, chemical burns, and factitious injections. Therefore, when confronted with a dermonecrotic lesion, the clinician should not rush to diagnose a spider bite without considering all of the potential causes (6). The massive eyelid edema and early necrosis observed in the case presented here are consistent with loxoscelism but not diagnostic, as other conditions, particularly envenomations from other arthropods, can have such a presentation.…”

“…The initial interaction between the venom and tissues causes complement activation, migration of polymorphic neutrophils, liberation of proteolytic enzymes, cy-tokine and chemokine release, platelet aggregation, and blood flow alterations that result in edema and ischemia, with development of necrosis (2). The first situation, which is more common (67-100%), is characterized by the presence of painful cutaneous lesion, of slow and gradual evolution, where signs such as edema, induration, erythema, ischemia, ecchymosis, and mixed area of erythema, ecchymosis, and ischemia, known as red, white, and blue sign, appear (3,5,6). Previous studies have reported that, over the next 5 days, there is a massive neutrophilic infiltration into the dermis and subcutaneous muscle, with vessel destruction, thrombosis, hemorrhage, myonecrosis, and coagulative necrosis (1).…”

Reconstructive considerations following a necrotic spider bite on the face: A case report

“…In six reported cases of necrotic lesions in the facial region caused by recluse spider bites (four on the eyelid, one on the chin and one on the ear), two patients underwent active reconstruction with a local flap and delayed suturing respectively, following an initial bout of healing by secondary intention. Complete healing in these two cases happened in 2 and 3 weeks respectively [12] , [13] . Time to complete healing in the remaining four cases exclusively let to heal by secondary intention, was 2 months (one patient; healed with no scarring [4] ) and 6 months respectively (three patients; healed with scarring [10] , [14] ).…”

“…Complete healing in these two cases happened in 2 and 3 weeks respectively [12], [13]. Time to complete healing in the remaining four cases exclusively let to heal by secondary intention, was 2 months (one patient; healed with no scarring [4]) and 6 months respectively (three patients; healed with scarring [10], [14]).…”

Sixty cases of extreme osteonecrosis and osteomyelitis of the mandible and maxilla in a West African population

“…Envenomation by the brown recluse spider (Loxosceles reclusa) in the facial area has been reported to cause significant soft tissue necrosis that usually resolves without surgical intervention. 36 Latrodectus (the Black Widow) produces a systemic toxic venom which results in abdominal cramps, convulsions, death and may also result in cutaneous lesions 37 .…”