Brooke–Spiegler syndrome – report of four families: treatment with CO<sub>2</sub> laser

Retamar, R. A.; Stengel, Fernando; Saadi, María Emilia; Kien, María Cristina; Giovana, P. Della; Cabrera, Hugo; Chouela, Edgardo

doi:10.1111/j.1365-4632.2007.01689.x

Cited by 42 publications

(24 citation statements)

References 15 publications

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“…Therefore, the complete surgical removal with free resection margins, as well as a close follow-up, is of great importance. In addition to the classic surgical resection, treatment with CO 2 laser has been reported, especially in cases with multiple cylindromas 8 17…”

Section: Discussionmentioning

confidence: 99%

Benign cylindroma: a rare differential diagnosis of external ear canal tumour

et al. 2016

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Cylindromas are rare adnexal skin tumours that usually occur in the head and neck area. This article reports a case of benign cylindroma arising in the external auditory canal. A 75-year-old man presented with a 3-month history of right aural fullness; no other symptoms were reported. Ear microscopy examination revealed a skin mass on the floor of the external ear canal. Α CT scan of the skull showed a well-circumscribed soft tissue mass, with no signs of underlying cortical bone erosion. Tumour resection through an endaural approach was performed. Histological examination revealed a benign cylindroma with margins free of tumour, so that no further treatment was necessary. 8 months after surgery the patient is asymptomatic with normal findings in the ear microscopy examination. Benign cylindroma has a high recurrence rate and can undergo malignant transformation. Therefore, complete surgical removal and close follow-up are of great importance.

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Section: Discussionmentioning

confidence: 99%

Benign cylindroma: a rare differential diagnosis of external ear canal tumour

et al. 2016

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“…Multiple cylindromas usually require extensive plastic surgery that may be obviated by progressively excising a group of nodules in multiple sittings. [415]…”

Section: Discussionmentioning

confidence: 99%

Solitary cylindroma with malignant transformation

et al. 2012

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A 59-year-old woman presented with a history of rapidly progressive recurrent tumor of 6.5 cm diameter of the scalp. Histopathological examination revealed a case of malignant cylindroma. There has been no recurrence or metastases and the patient is disease free at the end of 15 months postoperatively. Malignant transformation occurs less often in solitary form of cylindroma, but once transformed, tumors behave aggressively with extensive local infiltrative growth or metastases. The case is reported to document a rare case of malignant cylindroma arising in a patient with solitary cylindroma on the parieto-temporal region.

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“…Other treatments include scalping, Mohs' micrographic surgery, laser ablation, electrodessication/curettage, cryotherapy, trichloroacetic acid, retinoic acid, carbon dioxide laser, and radiotherapy [23]. Multiple cylindromas usually require extensive plastic surgery that may be obviated by progressively excising a group of nodules in multiple procedures [23].…”

Section: Discussionmentioning

confidence: 99%

Malignant Cylindroma of the Scalp Arising in a Setting of Multiple Cylindromatosis: A Case Report

Glavin

Bhattacharyya

2009

Head and Neck Pathol

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An unusual case of malignant cylindroma of the scalp arising in a 79-year-old white female with multiple cylindromatosis is presented. The tumor apparently arose from a cylindroma and had features of spiradenoma. Multiple cylindromatosis is an uncommon hereditary autosomal dominant disease, which is characterized by multiple skin adnexal tumors like cylindromas and trichoepitheliomas and occasional spiradenomas. Cylindroma is an uncommon benign tumor, which originates from skin appendages and is most commonly found on the scalp and face with a strong predilection for middle-aged and elderly females. Although cylindromas are usually benign neoplasms, carcinoma arising in such neoplasms is rare with only sporadic reports in literature. Her family history was negative for a similar disease. The patient's main concern was painful lesions over her right ear that interfered with wearing of her glasses. The clinical, histological immunohistochemical features, and treatment are presented along with a review of the literature.

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Brooke–Spiegler syndrome – report of four families: treatment with CO₂ laser

Abstract: The large number of facial lesions in this syndrome often produce a significant emotional impact. We believe that it is important to provide patients with a good therapeutic option. CO(2) laser therapy may fill this role.

Cited by 42 publications

References 15 publications

Benign cylindroma: a rare differential diagnosis of external ear canal tumour

Benign cylindroma: a rare differential diagnosis of external ear canal tumour

Solitary cylindroma with malignant transformation

Malignant Cylindroma of the Scalp Arising in a Setting of Multiple Cylindromatosis: A Case Report

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Brooke–Spiegler syndrome – report of four families: treatment with CO2 laser

Abstract: The large number of facial lesions in this syndrome often produce a significant emotional impact. We believe that it is important to provide patients with a good therapeutic option. CO(2) laser therapy may fill this role.

Cited by 42 publications

References 15 publications

Benign cylindroma: a rare differential diagnosis of external ear canal tumour

Benign cylindroma: a rare differential diagnosis of external ear canal tumour

Solitary cylindroma with malignant transformation

Malignant Cylindroma of the Scalp Arising in a Setting of Multiple Cylindromatosis: A Case Report

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Product

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Brooke–Spiegler syndrome – report of four families: treatment with CO₂ laser