Solitary cylindroma with malignant transformation

Bansal, Cherry; Batra, Mayanka; Lal, Nirupma; Srivastava, Aditi

doi:10.4103/0019-5154.94289

Cited by 11 publications

(10 citation statements)

References 12 publications

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“…The solitary form occurs as frequent as the multiple form or even more frequently. 10 Variant with multiple cutaneous cylindromas are inherited in an autosomal dominant manner. The observation of multiple cylindromas was first made by Brooke in 1892 and later by Spiegler in 1899.…”

Section: Discussionmentioning

confidence: 99%

Solitary dermal cylindroma: a rare case report

Widayati

Irianiwati

2019

JMedScie

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Dermal cylindromas are rare benign skin appendageal tumors that has two clinical presentation, solitary and multiple form. The diagnosis is unusual. However, it must be considered in clinical practice.A 51-year-old woman hadpainless nodule on right arm. Skin examinatipn revealedtwo fragmented nodules, 1x0.5x0.5cm, tan to white, and rubbery. Histopathological findings revealed a well demarcated and an unencapsulated epithelial dermal tumor, composed of numerous oval and polygonal nests molded into a "jig-saw" or "mosaic" appearance at low power. The nests of cells were composed of basaloid cells with scant cytoplasm and hyperchromatic nuclei and paler cells at the center. Nests of epithelial cells were surrounded and penetrated by a thickened band of basement membrane material that was PAS-positive. Immunohistochemistry (IHC) staining with p63 showed positive staining on basaloid cells. Langerhans dendritic cells in the surrounding nests stained positive with CD1a. Solitary dermal cylindroma occurred sporadically in patients without family history of cutaneous cylindromas.Combination of morphologic, histochemystry and immunohistochemystry staining were needed for accurate diagnosis.

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Section: Discussionmentioning

confidence: 99%

Solitary dermal cylindroma: a rare case report

Widayati

Irianiwati

2019

JMedScie

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“…Similarly to spiradenocarcinoma, cylindrocarcinoma is an extremely rare tumour which has been described in the setting of solitary lesions, but more commonly in association with multiple cylindromas . Cylindrocarcinoma is more common on the scalp, and its clinical features include rapid growth, bleeding, ulceration and/or colour change in a pre‐existing lesion …”

Section: Cylindrocarcinoma (Malignant Cylindroma)mentioning

confidence: 99%

Malignant sweat gland tumours: an update

Cardoso

Calonje

2015

Histopathology

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Cutaneous adnexal tumours can be a diagnostic challenge for the pathologist. This is particularly true in the case of tumours with sweat gland differentiation, due to a large number of rare entities, a multiplicity of names to designate the same neoplasms and consequent lack of consensus regarding their classification and nomenclature. In the traditional view, sweat gland tumours were divided into eccrine and apocrine. However, this has been challenged in recent years, and in fact many of these tumours may have both eccrine and apocrine variants. Some display more complex features and defy classification, due to the presence of other lines of differentiation, namely follicular and/or sebaceous (in the case of apocrine tumours, due to the close embryological relationship between apocrine glands, hair follicles and sebaceous glands). The present paper reviews and updates the basic concepts regarding the following malignant sweat gland tumours: apocrine carcinoma, porocarcinoma, hidradenocarcinoma, spiradenocarcinoma, cylindrocarcinoma, microcystic adnexal carcinoma and related entities, squamoid eccrine ductal carcinoma, digital papillary adenocarcinoma, primary cutaneous mucinous carcinoma, endocrine mucin-producing sweat gland carcinoma and primary cutaneous signet ring cell carcinoma. Particular emphasis is put in recent findings that may have implications in the diagnosis and management of these tumours.

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“…Malignant transformation is extremely uncommon [5] . Histopathologically, cylindromas are seen as circumscribed dermal or subcutaneous lesions.…”

Section: Discussionmentioning

confidence: 99%

Cryotherapy as a method of choice in the treatment of cylindromas on the elderly

Brzeziński

Sousak²,

Ortíz

et al. 2016

J Surg Dermatol

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Abstract:The elderly (i.e., geriatric group) are often vulnerable to skin cancer. These patients often cannot cope with biopsies and surgical excisions. A good alternative is cryotherapy. Cylindroma is a benign adnexal tumor of the skin with eccrine and apocrine differentiation, and commonly occurs in the scalp. We present the case of an 82-year-old woman with a number of large tumors located on the head, which were effectively removed via cryotherapy with liquid nitrogen as a palliative treatment. No recurrence was detected during the two-year follow-up. Cryotherapy with liquid nitrogen is an effective and non-invasive method for the treatment of benign skin tumors in the elderly.Keywords: Skin cancer; cryotherapy; tumor, elderly; cylindroma; carcinoma Citation: Brzezinski P, Sousak M, Di Martino Ortiz B, Chiriac A. Cryotherapy as a method of choice in the treatment of cylindromas on the elderly.

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Solitary cylindroma with malignant transformation

Cited by 11 publications

References 12 publications

Solitary dermal cylindroma: a rare case report

Solitary dermal cylindroma: a rare case report

Malignant sweat gland tumours: an update

Cryotherapy as a method of choice in the treatment of cylindromas on the elderly

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