Bronchoconstriction-triggered cough in atopic cough: A retrospective study

Ohkura, Noriyuki; Hara, Johsuke; Sakai, Tamami; Okazaki, Akihito; Abo, Masahiro; Kondo, Kazuo; Fujimura, Masaki

doi:10.1080/01902148.2016.1195460

Cited by 5 publications

(2 citation statements)

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“…AC was first proposed by Japanese scholars Fujimura and others [18] in 1992, and was later found to be one of the main etiologies of chronic cough in Japan. [4] AC children patients are often atopic physiques, and better efficacy can be obtained by antihistamines therapy (be careful to distinguish with non-asthmatic eosinophilic bronchitis, the relative percentage of the eosinophil in the sputum of the later was more than 3%, and the anti-histamine drugs are ineffective). [19] Increased sensitivity of cough receptor is the key to diagnose AC.…”

Section: Discussionmentioning

confidence: 99%

Etiology analysis of nonspecific chronic cough in children of 5 years and younger

Chen

Peng²,

Wang³

2019

Medicine

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This study aims to analyze the etiology of nonspecific chronic cough in children of 5 years and younger, in order to improve the diagnostic and treatment levels of pediatricians for nonspecific chronic cough in young children.The clinical data of 85 cases of children of 5 years old and below, who suffered from nonspecific chronic cough between the period of January 2015 and August 2016 were retrospectively analyzed.The etiology distribution of 85 cases of children with nonspecific chronic cough were as follows: 27 cases had cough variant asthma (31.8%), 32 cases had upper airway cough syndrome (37.6%), 16 cases had cough after infection (18.8%), 3 cases had gastroesophageal reflux cough (3.5%), 2 cases had allergic cough (2.4%), and 5 cases had unknown causes of cough (5.9%).The main composition ratio of the etiology of chronic cough in children of 5 years old and below is as follows (in sequence): upper airway cough syndrome, cough variant asthma, and post infection cough.

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Section: Discussionmentioning

confidence: 99%

Etiology analysis of nonspecific chronic cough in children of 5 years and younger

Chen

Peng²,

Wang³

2019

Medicine

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“…Cough reflex is mediated by two classes of sensory neurons which respond to mechanical stimuli and chemical stimuli such as capsaicin and bradykinin to varying degrees (25). Indeed, cough reflex sensitivity is enhanced in patients with several diseases (25)(26)(27)(28)(29)(30). Therefore, clinicians should also pay special attention to the triggers of cough.…”

Section: Discussionmentioning

confidence: 99%

A Cross-sectional Survey of the Clinical Manifestations and Underlying Illness of Cough

Otoshi

Nagano

Funada

et al. 2019

In Vivo

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Aim: The aim of this study was to identify factors affecting the final diagnosis of cough. Materials and Methods: This study recruited 463 consecutive patients who visited five Japanese general hospitals due to cough from October 2006 to September 2007. Of these, 418 patients (90%) who completed a questionnaire designed to acquire data regarding clinical manifestations of cough were included. Results: Most patients with bronchial asthma had cough with seasonal variation and wheezing. Patients with gastro esophageal reflux disease suffered from heartburn and cough without daily or seasonal variation. Cough associated with sinobronchial syndrome was only observed in females and was linked to increased sputum. Patients with whooping cough were bothered by cough interrupting sleep and talking. Patients with cardiogenic cough had exertional dyspnea. Conclusion: The specific items on our questionnaire relating to patient characteristics, complications, and triggers of cough, represent useful tools for diagnosing the primary disease producing cough.Cough is one of the most common reasons for hospital visits (1) and has a substantial impact on quality of life (for example, sleep disturbances or depression) and the use of healthcare resources (2-4). Cough is categorized according to its duration of symptoms: acute (0-2 weeks), sub-acute (3-7 weeks) and chronic (more than 8 weeks) (5). Previous studies have reported that the causes of acute and sub-acute cough are mostly acute respiratory infection and postinfection cough (1, 6), while the proportion of patients suffering from cough due to non-infectious diseases increases as the duration of cough increases (1). However, the causes of cough may vary in patients living in different geographical regions or among those of different ethnicities (7). While some existing reports focus on patients with chronic cough attending hospitals in Japan (8-11), very few studies have attempted to investigate the causes of cough among patients visiting hospitals with different types of cough (acute, sub-acute and chronic) (1). Moreover, little is known about the specific clinical manifestations of cough. The aim of this study was to clarify the clinical manifestations of cough, investigate the causative disorders involved, and identify factors affecting the final diagnosis of cough in an urban Japanese population. Materials and MethodsClinical institutions and participants. This was a cross-sectional survey performed between

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Methacholine-induced cough as an indicator of bronchodilator-responsive cough

Ohkura

Fujimura

Hara

et al. 2020

Pulmonary Pharmacology & Therapeutics

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Bronchoconstriction-triggered cough in atopic cough: A retrospective study

Abstract: The cough response to bronchoconstriction is reduced in AC compared to CVA. This feature may be useful in the diagnosis of chronic cough.

Cited by 5 publications

References 21 publications

Etiology analysis of nonspecific chronic cough in children of 5 years and younger

Etiology analysis of nonspecific chronic cough in children of 5 years and younger

A Cross-sectional Survey of the Clinical Manifestations and Underlying Illness of Cough

Methacholine-induced cough as an indicator of bronchodilator-responsive cough

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