1988
DOI: 10.1136/thx.43.9.735
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Bronchiolitis obliterans organising pneumonia in a patient with ulcerative colitis.

Abstract: A young woman with ulcerative colitis developed pneumonia, which responded to corticosteroids. Histological examination showed this to be bronchiolitis obliterans organising pneumonia. We are grateful to Professor B Corrin, Brompton Hospital, London, for reviewing the lung biopsy specimen.

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Cited by 87 publications
(36 citation statements)
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“…Based on these and the temporal relationship, the most likely cause of BOOP in this patient is probably still the lung cancer and/or the surgery itself. BOOP has been well reported to be associated with some auto-immune disorders, suggesting an immune-mediated mechanism [7,8]. In our case, the lung cancer might have presented some antigenic stimuli, which activated the host's immune system such that the inflammatory process perpetuated itself even after the surgical removal of the tumour.…”
Section: Discussionmentioning
confidence: 63%
“…Based on these and the temporal relationship, the most likely cause of BOOP in this patient is probably still the lung cancer and/or the surgery itself. BOOP has been well reported to be associated with some auto-immune disorders, suggesting an immune-mediated mechanism [7,8]. In our case, the lung cancer might have presented some antigenic stimuli, which activated the host's immune system such that the inflammatory process perpetuated itself even after the surgical removal of the tumour.…”
Section: Discussionmentioning
confidence: 63%
“…Secondly, even though such digestive disease as ulcerative colitis may associate with BOOP or with CEP [14,15], to the best of our knowledge, no case of BOOP has been described in association with an oesophageal diverticulum.…”
Section: Discussionmentioning
confidence: 99%
“…BOOP may be classified into three categories according to its etiology: organizing pneumonia of determined cause, organizing pneumonia of undetermined cause but occurring in a specific and relevant context, and cryptogenic (idiopathic) organizing pneumonia (9). BOOP can be seen in UC due for several reasons, such as reaction to viral, bacterial and fungal infections, the IBD itself, or drug reactions (10)(11)(12)(13). Persistent airway inflammation can result in airway narrowing, dependent on the localization, resulting in tracheal stenosis, bronchiectasis or bronchiolitis obliterans.…”
Section: Discussionmentioning
confidence: 99%