Bronchiectasis in Childhood

Bronchiectasis: Abated or Aborted?

“…The patients were school age children who usually experienced the onset of symptoms in early childhood. The association with a severe or with repeated infectious insults at an early age is consistent with the observations of other series [5] . For nearly one third of the children, Karadag determined the cause to be postinfectious.…”

“…The taboos against consanguinity are not as strong in many parts of the world where bronchiectasis is also more common. For example, the incidence of bronchiectasis among Alaska Native children in the Yukon-Kuskokwim delta region may be as high as 140/10,000 contrasted with 1/10,000 in another continental US series [5,7] . Alaska is one of a handful of states in the US where marriage between fi rst cousins is legal.…”

British Thoracic Society guideline for non-CFbronchiectasis

“…A positive sputum culture for an unusual bacterial organism can indicate an underlying disorder associated with bronchiectasis, in particular Staphylococcus aureus , Pseudomonas aeruginosa and non-tuberculous mycobacteria (CF or primary cilia dyskinesia55) or Burkholderia cepacia complex (chronic granulomatous disease or CF). Some organisms have a propensity to cause long-term sequelae; for example, particular serotypes of adenovirus (7, 14, 21)217 or Bordetella pertussis and any episode of severe pneumonia (whatever the cause) should prompt further investigation, particularly if there is incomplete resolution of symptoms or persistent physical signs 53 213. Recurrent (two or more) episodes of consolidation and either localised or multifocal212 213 persistent and unexplained chest radiographic abnormalities (suggestive of airway disease or a focal abnormality23) 12 weeks beyond the initial illness should also raise suspicion.…”

Bronchiectasis: a Cause of Pulmonary Symptoms in Heroin Addicts

“…Bronchiectasis may arise in childhood in association with congenital abnormalities [12], mucoviscidosis, immune deficiency [ 13], or viral infection [14]; this was not the case in our patients. None reported a histo ry of significant childhood respiratory dis ease and all dated the onset of symptoms subsequent to their addiction and, more spe cifically, following an episode of heroin in toxication resulting in hospitalization.…”