Bronchiectasis: a Cause of Pulmonary Symptoms in Heroin Addicts

Banner, Arthur S.; Rodriguez, Justo; Sunderrajan, Ettayapuram V.; Agarwal, Mahesh; Addington, Whitney W.

doi:10.1159/000194033

Cited by 17 publications

(8 citation statements)

References 10 publications

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“…This characteristic distribution may be more easily appreciated at CT (Fig 5c). Bronchiectasis, which has been reported in some heroin addicts with a history of acute lung injury related to drug use, is probably related to recurrent infection and aspiration (16,17). .…”

Section: Aspiration Pneumoniamentioning

confidence: 99%

Thoracic Complications of Illicit Drug Use: An Organ System Approach

Gotway¹,

Marder²,

Hanks³

et al. 2002

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Illicit drug use constitutes a major health problem and may be associated with various thoracic complications. These complications vary depending on the specific drug used and the route of administration. Commonly abused drugs that may play a role in causing thoracic disease include cocaine, opiates, and methamphetamine derivatives. Intravenously abused oral medications may contain filler agents that may be responsible for disease. Thoracic complications may be categorized as pulmonary, pleural, mediastinal, cardiovascular, and chest wall complications. Pulmonary complications of drug abuse include pneumonia, cardiogenic edema, acute lung injury, pulmonary hemorrhage, and aspiration pneumonia. Filler agents such as talc may result in panacinar emphysema or high-attenuation upper-lobe conglomerate masses. The primary pleural complication of illicit drug use is pneumothorax. Mediastinal and cardiovascular complications of illicit drug use include pneumomediastinum, cardiomyopathy, myocardial infarction, aortic dissection, and injection-related pseudoaneurysms. Chest wall complications include diskitis and vertebral osteomyelitis, epidural abscess, necrotizing fasciitis, costochondritis, and septic arthritis. Categorization of thoracic complications of illicit drug use may facilitate understanding of these disorders and allow accurate diagnosis.

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Section: Aspiration Pneumoniamentioning

confidence: 99%

Thoracic Complications of Illicit Drug Use: An Organ System Approach

Gotway¹,

Marder²,

Hanks³

et al. 2002

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104

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“…5,6 Similar to our patient these chronic changes have lower lobe predominance. 7 On CTT findings there were ground glass areas accompanying with ILD and his inflammatory markers was high. As mentioned above frequency of seconder pulmonary infections rises in drug abuser so he had been treated with empiric antibiotics.…”

Section: Discussionmentioning

confidence: 97%

“…There are some studies about benefits of prednisolone but dose and duration are still unclear. 7 We have administrated 40 mg prednisolone intravenously for his bronchospasm and he responded well.…”

Section: Discussionmentioning

confidence: 97%

Interstitial Lung Disease in A 19 Years Old Male Related to Intravenous Heroin Addiction: Case Report

Kabalak¹,

Özdemir²

2016

Turkiye Klinikleri Arch Lung

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nterstitial lung disease (ILD) has a wide, complicated spectrum and has a quite variety of reasons. Drugs are one part of etiology however illicit drug usage is elusive. Use of heroin is wide spreading and it is available at low prices. Depending on the route of administration, complications and onset time of presenting symptoms are alters between patients.Pulmonary complications related to injected drugs are infection, noncardiogenic pulmonary edema, emphysema, interstitial pneumonia and fibrosis, bronchiectasis, pneumothorax, talcosis, bronchiolitis obliterans organizing pneumonia (BOOP) and pulmonary vascular disease. Case Report A AB BS S T TR RA AC CT T Inhaled or intravenous (IV) abuse of illicit drugs is a common health problem and has acute-chronic pulmonary complications depending on the administration route. IV administration may result many side effects depending on to drug's pharmacodynamics or contamination. A variety of radiological changes are predictable for pulmonary complications. Interstitial lung disease (ILD) is a rare manifestation of heroin addiction due to especially talcosis. Our patient had history of IV heroin usage for 5 years. His computed thorax tomography (CTT) revealed bibasiller interstitial changes. Other common reasons that can lead to this condition were excluded and ILD was dedicated to heroin addiction. Further investigation couldn't be done because of patient's refusal. Particularly in a young patient with ILD findings on CTT drug abuse should be remembered. We aim to report a young boy with interstitial lung disease thought to be about IV heroin injection.K Ke ey y W Wo or rd ds s: : Lung diseases, interstitial; substance-related disorders; heroin Ö ÖZ ZE ET T Yasa dışı ilaç kullanımı yaygın bir halk sağlığı problemi olmasının yanı sıra uygulanma şek-line bağlı olarak [inhalasyon ya da intravenöz (IV)] pulmoner komplikasyonlara yol açabilmekte-dir. İntravenöz kullanım sırasında hijyenik olmayan koşullar ve madde farmakodinamiğine bağlı olarak yan etkiler gelişebilmektedir. Bu komplikasyonlar çeşitli radyolojik görünümler ile karşı-mıza çıkmakta olup interstisyel akciğer hastalığı (İAH) gelişimi ise talk maddesine bağlı gelişen komplikasyonlardan biridir. Özellikle genç bir yetişkinde bilgisayarlı toraks tomografisinde (BTT) İAH bulguları saptandığında bilinen nedenler ekarte edildikten sonra madde kullanımı etiyolojide akla gelmelidir. Beş yıllık IV eroin kullanım öyküsü olup BTT'de İAH bulguları saptanan 19 yaşın-daki bir erkek hastayı bu anlamda sunmayı amaçladık.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Akciğer hastalıkları, interstisyel; madde kullanımına bağlı bozukluklar; eroin T Tu ur rk ki iy ye e K Kl li in ni ik kl le er ri i A Ar rc ch h L Lu un ng g 2 20 01 16 6; ;1 17 7( (1 1) ): :9 9--1 11 1 10ILD is a chronic complication occurring as an inflammatory response to talc. Although cocaine is the most susceptible agent, IV heroin is the other frequent reason. Granulomas, giant cells, focal fibrosis and angio-thrombosis are expected histopathologic...

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“…24 The recognized initiating events of primary bronchiectasis are listed in Table 1. 3,4,[24][25][26][27][28][29][30][31][32][33][34][35][36] In contrast to the just described presentation, bronchiectasis involving the upper lobes is a complication of tuberculosis or fungal infections. Such individuals generally do not produce purulent sputum other than related to their primary disease process leading to the term "dry bronchiectasis" (Fig.…”

Section: Clinicalmentioning

confidence: 99%

“…It should be performed in duplicate to assure reproducibil-178 32 6. Intravenous drug addicts [33][34][35]…”

Section: Clinicalmentioning

confidence: 99%