Bronchial Sensitivity Testing in Asthma: An Assessment of the Effect of Hyposensitization in House-Dust and Pollen-sensitive Asthmatic Subjects

Asthma: A Study in Prognosis of 1,000 Patients

“…This is in line with the experience of McAllen (1961), who studied the effect of treatment both by the subcutaneous and by the endobronchial routes: those who improved were found to have returned to their original condition in about six months. The conclusion must be that whatever part allergic sensitivity may play in the course of bronchial asthma, it is not a factor of major importance in long-term prognosis.…”

Significance of late reactions after bronchial challenge with house dust mite.

“…They provide the only method of making a precise allergy diagnosis (Aas, 1975;Bronsky and Ellis, 1969;Colldahl, 1952;Hill, 1974;Spector and Farr, 1974), and can be used to assess the efficacy of Significance of late reactions after bronchial challenge with house dust mite various antiasthma drugs (Altounyan, 1964) and of hyposensitization (Aas, 1971;McAllen, 1961). They have even been used as a means of administrating antigen for hyposensitization programmes (Herxheimer, 1951;McAllen, 1961). While most of the above studies have been on small groups of patients in experimental situations, Aas (1970) has experience of this procedure in routine diagnostic work on over 1000 children, involving nearly 10 000 inhalation tests.…”

House-dust Mite Asthma. Results of Challenge Tests on Five Criteria with Dermatophagoides pteronyssinus

“…Bronchial challenge tests were carried out with the closed circuit method (Herxheimer, 1951;McAllen, 1961). An extract of standard strength was introduced into the circuit by means of a nebulizer of very low output, and the dose of the antigen was varied by altering the time of inhalation.…”