1988
DOI: 10.1001/archpedi.1988.02150070040021
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Bronchial Reactivity in Diabetic Patients

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Cited by 37 publications
(4 citation statements)
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“…The functional pattern described by this study was consistent with decreased lung elastic recoil, caused by prolonged hyperglycemia resulting in excessive non-enzymatic glycosylation of connective tissue [27,46,47], and with diminished elasticity. This is because FVC was impaired and the RV/TLC ratio was higher than in controls (p = 0.0002), even at the onset of disease (p = 0.04), without evidence of reduced FEV1/FVC or TLC.…”
Section: Pulmonary Function In Children and Adolescents With T1dsupporting
confidence: 79%
See 1 more Smart Citation
“…The functional pattern described by this study was consistent with decreased lung elastic recoil, caused by prolonged hyperglycemia resulting in excessive non-enzymatic glycosylation of connective tissue [27,46,47], and with diminished elasticity. This is because FVC was impaired and the RV/TLC ratio was higher than in controls (p = 0.0002), even at the onset of disease (p = 0.04), without evidence of reduced FEV1/FVC or TLC.…”
Section: Pulmonary Function In Children and Adolescents With T1dsupporting
confidence: 79%
“…Similarly, the reduction of FEV1 initially reported by Cazzato and Villa [46], was not confirmed by later studies conducted by Verrotti, Van Gelt, Al Saadi, and Villa himself [39,41,43].…”
Section: Pulmonary Function In Children and Adolescents With T1dmentioning
confidence: 77%
“…[19] Autonomic and phrenic neuropathy causing alterations in bronchial reactivity and respiratory muscle function was also suggested in one study. [23]…”
Section: Discussionmentioning
confidence: 99%
“…Decrease in FEV, is expressed as percentage of predicted (pred) FEV,. 30/15, ratio of 30th R-R interval to 15th R-R interval after moving from supine to erect posture; Rs, Spearman's rank correlation coefficient; • , diabetic patients without cardiac autonomic dysfunction (CAD); O, diabetic patients with CAD.children with IDDM compared with nondiabetic control children has been reported(17). Carbachol and methacholine are stable analogues of acetylcholine that directly act on bronchial smooth muscle, and methacholine challenge ap-Correlation between deep breathing-induced heart-rate changes (maximum -minimum heart rate) and forced expiratoryvolume in 1 s (FEV,) on methacholine challenge in diabetic patients.…”
mentioning
confidence: 99%