Bronchial Asthma and Hyperreactivity After Early Childhood Bronchiolitis or Pneumonia

Korppi, Matti; Kuikka, Liisa; Reijonen, Tiina M.; Remes, Kyllikki; Juntunen‐Backman, Kaisu; Launiala, K

doi:10.1001/archpedi.1994.02170100077015

Cited by 92 publications

(152 citation statements)

References 26 publications

Supporting

Mentioning

140

Contrasting

Order By: Relevance

“…In fact, vitamin D deficiency has been shown to predispose children to respiratory infections [31][32][33], and vitamin D supplements have been shown to decrease the incidence of respiratory infections [34]. This may have obvious consequences, as early respiratory infections may predispose to the onset of asthma [35][36][37][38] and the development of bronchial hyperreactivity [39]. However, no evaluation of the prevalence of respiratory infections was performed on our cohort.…”

Section: Discussionmentioning

confidence: 99%

Serum vitamin D levels and exercise-induced bronchoconstriction in children with asthma

Chinellato¹,

Piazza²,

Sandri³

et al. 2010

European Respiratory Journal

View full text Add to dashboard Cite

Epidemiological studies have established a relationship between low levels of serum vitamin D and reduced lung function in healthy adults, and asthma onset and severity in children. However, no study has examined the relationship between vitamin D levels and exercise-induced bronchoconstriction in asthmatic children.We evaluated the relationship between 25-hydroxyvitamin D concentrations and baseline forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1) and change in FEV1 (DFEV1) after a standardised exercise challenge in 45 children with intermittent asthma.Only 11% of the children had desirable serum vitamin D levels (at least 30-40 ng?mL Our results indicate that hypovitaminosis D is frequent in asthmatic children who live in a Mediterranean country. In those children, lower levels of vitamin D are associated with reduced lung function and increased reactivity to exercise.

show abstract

Section: Discussionmentioning

confidence: 99%

Serum vitamin D levels and exercise-induced bronchoconstriction in children with asthma

Chinellato¹,

Piazza²,

Sandri³

et al. 2010

European Respiratory Journal

View full text Add to dashboard Cite

show abstract

“…In an effort to cover the lifetime history of moisture damage, the current study focused on young children, among whom asthma is often of a transient nature [12,13]. In the present study, new cases of asthma were recruited from a hospital clinic by a paediatrician and were required to have had at least two doctor-diagnosed attacks of wheezing.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, despite their young age, most of the children in the present study are likely to have persistent asthma. The association between moisture damage and asthma was explored separately by age (f30 months or .30 months) and atopy, as wheezing in the first 3 yrs of life and among nonatopics has been reported to be transient more often than wheezing in later life and among atopics [12,13]. The associations were found to be comparable among atopic and nonatopic asthmatics and among those with early and late onset of the disease, further suggesting that moisture damage at home not only exacerbates asthma symptoms, but is also involved in the development of persistent asthma.…”

Section: Discussionmentioning

confidence: 99%

“…Most of these studies [5,[8][9][10][11] have been based on birth cohort studies that have followed the children only to the age of 1 or 2 yrs, which makes them difficult to interpret given the transient nature of asthma-related symptoms in early age [12,13]. A case-control study of prevalent asthma reported an association between self-reported, but not observed, damp and mould [4].…”

mentioning

confidence: 99%

“…The severity and location of moisture damage were assessed during a detailed home visit by trained civil engineers. In addition to overall analyses, atopic versus nonatopic asthmatics and those with early-versus late-onset asthma were analysed separately, as atopic, lateonset asthma is more likely to persist [12,13].…”

mentioning

confidence: 99%

See 2 more Smart Citations

Moisture damage and childhood asthma: a population-based incident case-control study

Pekkanen¹,

Hyvärinen²,

Haverinen‐Shaughnessy³

et al. 2007

European Respiratory Journal

137

107

View full text Add to dashboard Cite

Most previous studies on the association between moisture damage and asthma have been cross-sectional and relied on self-reported exposure and health. The present authors studied the association by carrying out careful home inspections among new, clinically determined cases of asthma and controls.New cases of asthma aged 12-84 months (n5121) were recruited prospectively and matched for year of birth, sex and living area with two randomly selected population controls (n5241). Trained engineers visited all homes. Both cases and controls had lived o75% of their lifetime or the past 2 yrs in their current home.Risk of asthma increased with severity of moisture damage and presence of visible mould in the main living quarters but not in other areas of the house. Cases more often had damage in their bedroom. Associations were comparable for atopic and nonatopic asthma and for children aged .30 months or f30 months.The present results, using standardised assessment of exposure and asthma, suggest that moisture damage and mould growth in the main living quarters are associated with the development of asthma in early childhood.

show abstract

Prospective Follow-up and Pulmonary Functions From a Placebo-Controlled Randomized Trial of Ribavirin Therapy in Respiratory Syncytial Virus Bronchiolitis

Rodríguez

Arrobio²,

Fink³

et al. 1999

Arch Pediatr Adolesc Med

View full text Add to dashboard Cite

show abstract

Bronchial Asthma and Hyperreactivity After Early Childhood Bronchiolitis or Pneumonia

Cited by 92 publications

References 26 publications

Serum vitamin D levels and exercise-induced bronchoconstriction in children with asthma

Serum vitamin D levels and exercise-induced bronchoconstriction in children with asthma

Moisture damage and childhood asthma: a population-based incident case-control study

Prospective Follow-up and Pulmonary Functions From a Placebo-Controlled Randomized Trial of Ribavirin Therapy in Respiratory Syncytial Virus Bronchiolitis

Contact Info

Product

Resources

About