Brenner Tumours of the Ovary

Malignant Brenner Tumor of the Ovary: A Systematic Review of the Literature

“…The publication years ranged from 1956 to 2023. The age in 108/115 (93.9%) cases [ 2 , 8 , 9 , 10 , 11 , 12 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 ] was reported. Specifically, the mean age at presentation was 59 ± 13 years, ranging from 22 to 87 years.…”

“…Specifically, the mean age at presentation was 59 ± 13 years, ranging from 22 to 87 years. Presenting symptoms were reported in 113/115 (98.3%) patients [ 2 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 ]. The most common presenting symptom was abdominal pain, which was present in 42/113 patients (37.1%) [ 2 , 13 , 19 , 22 , 26 , 27 , …”

“…Other symptoms included diarrhea (2/113, 1.8%) [ 15 , 18 ], constipation (2/113, 1.8%) [ 44 , 47 ], hematuresis (1/113, 0.9%) [ 40 ] and acute urinary retention (1/113, 0.9%) [ 17 ]. Ascites was present in 33/113 (29.2%) cases [ 9 , 13 , 20 , 24 , 25 , 26 , 27 , 29 , 31 , 34 , 36 , 38 , 39 , 40 , 42 , 43 , 44 , 46 , 48 , 53 ]. The patient presented by Baizabal-Carvallo et al, had a bifrontal headache, tinnitus, blurred vision, and dizziness due to dural metastasis [ 33 ].…”

“…Data concerning laterality were provided in 97/115 (84.3%) cases [ 2 , 8 , 9 , 10 , 11 , 12 , 14 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 42 , 43 , 44 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 ]; 45/97 (46.4%) cases involved the right ovary [ 2 , 9 , 16 , 17 , 18 , 21 , 24 , 25 , 26 , 29 , 30 , …”

“…One patient was not staged due to her poor medical status [ 35 ]. Staging was not mentioned in 14/115 (12.1%) cases [ 9 , 11 , 12 , 14 , 15 , 16 , 19 , 25 , 32 , 37 , 41 , 43 , 46 ]. The details of the staging are presented in Supplementary Table S3 .…”