Breed and site predispositions of dogs with atopic dermatitis: a comparison of five locations in three continents

Abstract

The objectives of this multicentre study were to analyse and compare breed predispositions and lesion distributions of 552 dogs diagnosed with atopic dermatitis from five different dermatologic referral centres located in Australia, Germany (2) and the United States (2). Breeds were compared with the canine population in the respective locations. Breed predispositions varied from geographical site, although golden retrievers and German shepherd dogs were predisposed in three of five practices. Lesions were present most commonly on the paws (62%), ventrum (51%), ears (48%) and face (39%). Various breeds had specific site predilections. Based on this study, breed predispositions can vary greatly both between continents and also between different locations on the same continent. In addition, some breeds showed predispositions for certain body sites which also varied in some instances with the geographical location.

Canine atopic dermatitis in the Middle East: clinical signs, signalment and common allergens

“…In our study otitis externa was found in 49% of the dogs. Very similar findings were recently reported in surveys from five locations on three continents (Jaeger et al 2010) and also to other studies from Greece and Switzerland (Saridomichelakis et al 1999;Picco et al 2008).…”

“…Our data did not show any associations between breeds and the distribution of the other lesions of CAD, however, such associations have been reported (Picco et al 2008;Jaeger et al 2010;Wilhem et al 2011). The clinical significance of these findings is unclear, however, and none of these associations was included in the new criteria for the diagnosis of CAD (Favrot et al 2010).…”

“…Otitis externa was the most frequent clinical sign in atopic Labradors and Golden Retrievers and their crosses in another study (Fraser et al 2008). In a survey on dogs with CAD from three continents, Beagles, French Bulldogs, GSDs and Jack Russell terriers with otitis externa were presented significantly more (Jaeger et al 2010). In another recent study boxers were reported to be highly affected with otitis (Wilhem et al 2011).…”

“…Although less frequent than those on the ventrum, lesions on the feet were also very common in the studied population. Feet lesions were Fischer-exact test showed that dogs with otitis externa were less allergic to feathers than to other allergens P < 0.05 c Kruskal-Wallis test revealed significant difference between golden retriever, boxers, shar-peis and mix breeds that had more positive reactions to trees than other breeds P < 0.05 d Mann-Witney test showed that dogs that with otitis externa had more positive reactions to dust than to other allergens P < 0.05 Table 4 continued documented as the most common site in many other surveys from Europe, North America, Australia and Asia (Saridomichelakis et al 1999;Zur et al 2002;Chanthick et al 2008;Jaeger et al 2010), and recently they were also considered as a validating criterion for the diagnosis of CAD (Favrot et al 2010). In this report, lesions on the ear pinnae, but not pinnal margins were also a validating criterion for CAD.…”

“…Nevertheless, belonging to one of these For groups' details see Table 1 *43 dogs were not tested for cotton seeds breeds was not a parameter for inclusion in the new criteria (Favrot et al 2010). The Labrador Retriever and the Golden Retriever were found to have a very high predilection for CAD in several studies from North America, Europe and Australia (Zur et al 2002;Nodtvedt et al 2007;Jaeger et al 2010). These breeds showed a strong heritability for the disease (Shaw et al 2004).…”