Breastfeeding of infants born to mothers with COVID-19: a rapid review

Yang, Nan; Che, Siyi; Zhang, Jingyi; Wang, Xia; Tang, Yuyi; Wang, Jianjian; Huang, Liping; Chen, Zhong; Zhang, Hairong; Baskota, Muna; Ma, Yanfang; Zhou, Qi; Luo, Xufei; Yang, Shu; Feng, Xiangyu; Li, Weiguo; Fukuoka, Toshio; Ahn, Hyeong Sik; Lee, Myeong Soo; Luo, Zhengxiu; Liu, Enmei; Chen, Yaolong; Evidence, Covid

doi:10.21037/atm-20-3299

Cited by 48 publications

(35 citation statements)

References 29 publications

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“…Infected mothers must continue taking suitable precautions to decrease the probability of virus transmission through close contact and droplets during breastfeeding. [14][15] Early and precise diagnosis of COVID-19 is fundamental to save people's lives. False negative test results could accelerate the spread of the disease in the community while false positive results could lead to starting unnecessary therapy and mental trauma to the patients and families.…”

Section: ____________________________________________________________mentioning

confidence: 99%

A Brief view on the pediatric COVID- 19 pandemic

Obaid¹,

Subhi²,

Al-Zwaini³

et al. 2020

Al-Kindy Col. Med. J

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The world is currently challenging the serious effects of the pandemic of the Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Data on pediatric COVID are rare and scattered in the literature. In this article, we presented the updated knowledge on the pediatric COVID-19 from different aspects. We hope it will increase the awareness of the pediatricians and health care professionals on this pandemic.

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Section: ____________________________________________________________mentioning

confidence: 99%

A Brief view on the pediatric COVID- 19 pandemic

Obaid¹,

Subhi²,

Al-Zwaini³

et al. 2020

Al-Kindy Col. Med. J

View full text Add to dashboard Cite

show abstract

“…This is because, even though the maternal showed positive towards SARS-CoV, the breast feeding without any protective measures showed negative COVID result on the infant. The same was denoted for the influenza virus detection but the authors ensure the distancing between the mother and infant as the impact of viral infection is not clear through investigation [51]. Similar to these reports, the studies by Lackey et al also did not trace the presence of SARS-CoV-2 in infants spread through breast milk but the vertical transmission was discussed [52].…”

Section: Human Coronavirus and Their Structuresmentioning

confidence: 89%

Current methods for diagnosis of human coronaviruses: pros and cons

et al. 2020

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The current global fight against coronavirus disease (COVID-19) to flatten the transmission curve is put forth by the World Health Organization (WHO) as there is no immediate diagnosis or cure for COVID-19 so far. In order to stop the spread, researchers worldwide are working around the clock aiming to develop reliable tools for early diagnosis of severe acute respiratory syndrome (SARS-CoV-2) understanding the infection path and mechanisms. Currently, nucleic acid-based molecular diagnosis (real-time reverse transcription polymerase chain reaction (RT-PCR) test) is considered the gold standard for early diagnosis of SARS-CoV-2. Antibody-based serology detection is ineffective for the purpose of early diagnosis, but a potential tool for serosurveys, providing people with immune certificates for clearance from COVID-19 infection. Meanwhile, there are various blooming methods developed these days. In this review, we summarise different types of coronavirus discovered which can be transmitted between human beings. Methods used for diagnosis of the discovered human coronavirus (SARS, MERS, COVID-19) including nucleic acid detection, gene sequencing, antibody detection, antigen detection, and clinical diagnosis are presented. Their merits, demerits and prospects are discussed which can help the researchers to develop new generation of advanced diagnostic tools for accurate and effective control of human coronavirus transmission in the communities and hospitals.

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“…In our research, the infant was most likely infected by his mother, and we cannot rule out the possibility that the infant acquired his infection from breastfeeding. Thus far, the transmission of SARS−COV-2 from mother to child has been controversial [ 23 ]. Some researchers [ 24 , 25 ] have found that SARS−COV-2 is not transmitted to infants through breast milk, amniotic fluid or placenta, but other studies [ 9 , 26 ] have shown that antibodies and viral RNA can be detected in breast milk, which suggests a possible mother -to -child transmission of the virus.…”

Section: Discussionmentioning

confidence: 99%

Coronavirus disease-2019 (COVID-19) infection in a 3-month-old infant: Clinical features, treatment and probable route of transmission

Wei

Liu

Yuan

et al. 2020

IDCases

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This study aims to explore the clinical and epidemiological characteristics of infant patients with coronavirus disease-2019 (COVID-19) infection. Clinical and epidemiological data of a 3-month-old patient with COVID-19 were collected, including general status, clinical results, laboratory tests, imaging characteristics, and epidemiological reports. The infant had no fever but had mild respiratory symptoms. The major laboratory results included normal white blood cell counts and lymphocytopenia, notably with elevated interleukin (IL-)-17A, IL-17F, and tumor necrosis factor (TNF-)-α. The main manifestation of his chest computed tomography scan was pulmonary patchy shadows. All throat swabs and urine of the infant detected via Real-time Quantitative Polymerase Chain Reaction (RT-PCR) were negative, but his anal swab continued to test positive up to 40 days after onset of illness. Our study indicated that infants infected with COVID-19 may have relatively mild symptoms or clinical signs, IL-17A, IL-17 F, and TNF-α could be involved in the immune response of COVID-19. In addition, severe acute respiratory syndrome coronavirus 2( SARS-CoV-2 ) may shed through the gastrointestinal tract and convalescent carriers may exist among infant patients. We cannot rule out the possibility that infants may acquire infection from breastfeeding. Intensive care and nutrition support are recommended for infant patients with mild symptoms.

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Breastfeeding of infants born to mothers with COVID-19: a rapid review

Abstract: Background: Existing recommendations on whether mothers with COVID-19 should continue breastfeeding are still conflicting. We aimed to conduct a rapid review of mother-to-child transmission of COVID-19 during breastfeeding.

Cited by 48 publications

References 29 publications

A Brief view on the pediatric COVID- 19 pandemic

A Brief view on the pediatric COVID- 19 pandemic

Current methods for diagnosis of human coronaviruses: pros and cons

Coronavirus disease-2019 (COVID-19) infection in a 3-month-old infant: Clinical features, treatment and probable route of transmission

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