Breast Reconstruction and Revision Surgery for Implant-associated Breast Deformities Using Porcine Acellular Dermal Matrix: A Multicenter Study of 156 Cases

Hille-Betz, Ursula; Kniebusch, Nadine; Wojcinski, Sebastian; Henseler, Helga; Heyl, V.; Öhlinger, R.; Paepke, Stefan; Klapdor, Rüdiger; Krause-Bergmann, B

doi:10.1245/s10434-014-4098-3

Cited by 25 publications

(30 citation statements)

References 37 publications

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“…After passing through the selection process, 20 studies fit the criteria and were analyzed (Fig. ) . Only one prospective study was found, and the others were retrospective.…”

Section: Resultsmentioning

confidence: 99%

“…Three studies representing 1,126 cases reported the results following nipple‐sparing mastectomy and the others did not specify the types of mastectomy. Twelve studies reported on two‐stage prosthetic reconstruction using a tissue expander, one regarding one‐stage direct‐to‐implant, and five using both methods. Four studies used ADM in all cases, six did not use it at all, and four used it selectively.…”

Section: Resultsmentioning

confidence: 99%

“…Twelve studies reported on two‐stage prosthetic reconstruction using a tissue expander, one regarding one‐stage direct‐to‐implant, and five using both methods. Four studies used ADM in all cases, six did not use it at all, and four used it selectively. Fourteen studies included immediate reconstruction cases, two included delayed cases, and the other two included both.…”

Section: Resultsmentioning

confidence: 99%

“…After passing through the selection process, 20 studies fit the criteria and were analyzed ( Fig. 1) [8,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32]. Only one prospective study [29] was found, and the others were retrospective.…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Prosthetic breast reconstruction in previously irradiated breasts: A meta‐analysis

Lee

Mun

2015

Journal of Surgical Oncology

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“…After passing through the selection process, 20 studies fit the criteria and were analyzed (Fig. ) . Only one prospective study was found, and the others were retrospective.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Prosthetic breast reconstruction in previously irradiated breasts: A meta‐analysis

Lee

Mun

2015

Journal of Surgical Oncology

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“…Overall capsular contracture rate in our retrospective study was 6%, including one patient with a history of chemotherapy and one patient with a history of radiotherapy. Within the current literature, capsular contracture rates after ADM implantation differ from 0 up to 3.75% [6, 11–19]. …”

Section: Discussionmentioning

confidence: 99%

Evaluation of Complication Rates after Breast Surgery Using Acellular Dermal Matrix: Median Follow-Up of Three Years

Paprottka

Krezdorn

Sorg

et al. 2017

Plastic Surgery International

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Introduction Acellular dermal matrices (ADMs) are now commonly used for breast reconstruction surgery. There are various products available: ADMs derived from human (HADM), porcine (PADM), or bovine (BADM) sources. Detailed long-term follow-up studies are necessary to detect differences in complication rates between these products. Material and Methods From 2010 to 2015, forty-one patients underwent 52 ADM-breast reconstructions in our clinic, including oncologic breast reconstructions and breast augmentation revisions (n = 52). 15x HADMs (Epiflex®/DIZG), 21x PADMs (Strattice®/LifeCell), and 16x BADMs (Tutomesh®/RTI Surgical) were implanted. Retrospective data collection with median follow-up of 36 months (range: 12–54 months) was performed. Results Overall complication rate was 17% after ADM implantation (HADM: 7%; PADM: 14%; BADM: 31%). In a composite endpoint of complications and Red Breast Syndrome, a lower event probability was observed between BADMs, PADMs, and HADMs (44%, 19%, and 7%, resp.; p = 0.01 for the trend). Furthermore, capsular contracture occurred in 6%, more frequently as compared to the current literature. Conclusions When ADM-based reconstruction is indicated, the authors suggest primarily the use of HADMs and secondary the use of PADMs. It is shown that BADMs have the highest complication probability within our patient cohort; nevertheless, BADMs convey physical advantages in terms of flexibility and better aesthetic outcomes. The indication for the use of ADMs should be filled for each case individually.

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Immediate Breast Reconstruction (Direct to Implant)

2017

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Breast Reconstruction and Revision Surgery for Implant-associated Breast Deformities Using Porcine Acellular Dermal Matrix: A Multicenter Study of 156 Cases

Abstract: Complication rates using porcine acellular dermal matrix in breast reconstruction are comparable to complication rates reported in studies using human acellular dermal matrices. Thus, porcine acellular dermal matrices can safely be applied in breast reconstructive surgery.

Cited by 25 publications

References 37 publications

Prosthetic breast reconstruction in previously irradiated breasts: A meta‐analysis

Prosthetic breast reconstruction in previously irradiated breasts: A meta‐analysis

Evaluation of Complication Rates after Breast Surgery Using Acellular Dermal Matrix: Median Follow-Up of Three Years

Immediate Breast Reconstruction (Direct to Implant)

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