“…Usually, the accuracy of IMRT delivery grows increasingly dependent on set-up errors and breathing motions. This is not an issue when standard 3D-CRT is used for isolated breast treatment, as the generous field design allows the target to remain in the field despite an inter- or intra-fraction motion [ 34 ]. At our institution, we only use vacuum fixation cushions for patients who undergo IMRT/VMAT to ensure positioning accuracy.…”