Breast Implants and Radiation

Mericli, Alexander F.; Sharabi, Safa E.

doi:10.1055/s-0039-1696963

Cited by 8 publications

(5 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another study by Reinders et al (mean follow-up: 21.75 months) reported an occurrence rate of Baker III-IV capsular fibrosis of 13/80 patients (16.9%) with a 13% rate of surgical revision, which is considerably lower than in our current study [8]. Nava et al reported in 109 patients (median follow-up: 50 months) a higher rate of capsular contracture of 57.8% without further differentiation regarding Baker classification; however, a considerably lower reconstructive failure rate of only 6.4% was detected [22,23]. It is widely accepted that PMRT following breast reconstruction is associated with an increased risk of secondary breast reconstruction surgery [24].…”

Section: Discussioncontrasting

confidence: 72%

Incidence and Risk Assessment of Capsular Contracture in Breast Cancer Patients following Post-Mastectomy Radiotherapy and Implant-Based Reconstruction

Vinsensia,

Schaub,

Meixner

et al. 2024

Cancers

View full text Add to dashboard Cite

Our study aims to identify the risk factors and dosimetry characteristics associated with capsular contracture. Methods: We retrospectively analyzed 118 women with breast cancer who underwent PMRT following an IBR between 2010 and 2022. Patients were treated with PMRT of 50.0–50.4 Gy in 25–28 fractions. Capsular contracture was categorized according to the Baker Classification for Reconstructed Breasts. Results: After a median follow-up of 22 months, the incidence of clinically relevant capsular contracture (Baker III–IV) was 22.9%. Overall, capsular contracture (Baker I–IV) occurred in 56 patients (47.5%) after a median of 9 months after PMRT. The rate of reconstruction failure/implant loss was 25.4%. In the univariate analysis, postoperative complications (prolonged pain, prolonged wound healing, seroma and swelling) and regional nodal involvement were associated with higher rates of capsular contracture (p = 0.017, OR: 2.5, 95% CI: 1.2–5.3 and p = 0.031, respectively). None of the analyzed dosimetric factors or the implant position were associated with a higher risk for capsular contracture. Conclusion: Postoperative complications and regional nodal involvement were associated with an increased risk of capsular contracture following breast reconstruction and PMRT, while none of the analyzed dosimetric factors were linked to a higher incidence. Additional studies are needed to identify further potential risk factors.

show abstract

Section: Discussioncontrasting

confidence: 72%

Incidence and Risk Assessment of Capsular Contracture in Breast Cancer Patients following Post-Mastectomy Radiotherapy and Implant-Based Reconstruction

Vinsensia,

Schaub,

Meixner

et al. 2024

Cancers

View full text Add to dashboard Cite

show abstract

“…Regarding immediate autologous reconstruction, they also have controversial results, but are shown to be less severe than immediate reconstructions with silicone implants (36) . Dewael et al (2019) 33 evaluated late complications in patients who performed immediate autologous reconstruction compared to patients who performed late (post-radiotherapy).…”

Section: Discussionmentioning

confidence: 99%

“…Regarding immediate autologous reconstruction, they also have controversial results, but are shown to be less severe than immediate reconstructions with silicone implants. 36 …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Interventions for Radiation-Induced Fibrosis in Patients With Breast Cancer: Systematic Review and Meta-analyses

Nogueira

Vital

Bernabé

et al. 2022

Advances in Radiation Oncology

View full text Add to dashboard Cite

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

show abstract

“…Radiation in the patient’s oncologic care is a well-known and well-studied risk factor for increased complications and reconstructive failure [ 5 , 6 ]. Since the appropriate management of cancer frequently requires radiation treatment (RT) to improve survival and recurrence rates, it is incumbent on the reconstructive surgeon to identify and implement strategies to compensate for this therapy.…”

Section: Introductionmentioning

confidence: 99%

Lipotransfer Strategies and Techniques to Achieve Successful Breast Reconstruction in the Radiated Breast

Crawford

Endara

2020

Medicina

View full text Add to dashboard Cite

Radiation therapy is frequently a critical component of breast cancer care but carries with it side effects that are particularly damaging to reconstructive efforts. Autologous lipotransfer has the ability to improve radiated skin throughout the body due to the pluripotent stem cells and multiple growth factors transferred therein. The oncologic safety of lipotransfer to the breasts is demonstrated in the literature and is frequently considered an adjunctive procedure for improving the aesthetic outcomes of breast reconstruction. Using lipotransfer as an integral rather than adjunctive step in the reconstructive process for breast cancer patients requiring radiation results in improved complication rates equivalent to those of nonradiated breasts, expanding options in these otherwise complicated cases. Herein, we provide a detailed review of the cellular toxicity conferred by radiotherapy and describe at length our approach to autologous lipotransfer in radiated breasts.

show abstract

Breast Implants and Radiation

Cited by 8 publications

References 72 publications

Incidence and Risk Assessment of Capsular Contracture in Breast Cancer Patients following Post-Mastectomy Radiotherapy and Implant-Based Reconstruction

Incidence and Risk Assessment of Capsular Contracture in Breast Cancer Patients following Post-Mastectomy Radiotherapy and Implant-Based Reconstruction

Interventions for Radiation-Induced Fibrosis in Patients With Breast Cancer: Systematic Review and Meta-analyses

Lipotransfer Strategies and Techniques to Achieve Successful Breast Reconstruction in the Radiated Breast

Contact Info

Product

Resources

About