Breast Implant-associated Anaplastic Large Cell Lymphoma – a Systematic Review with Pooled Analysis

Chan, TT; Ip, Kachanov; Lam, Henry; Ling, Gui; Ma, KK; Poon, C.T.; Yiu, O.L.; Yu, Hefen; Kwong, Ava

doi:10.1016/j.clon.2020.05.019

Cited by 4 publications

(3 citation statements)

References 66 publications

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“…Since then, there has been an expanding awareness of this substance 1 . Implants can be categorized into saline-filled, silicone-filled, or mixed, with smooth or textured 2 . The Food and Drug Administration (FDA) announced in 2011 that there could be a connection between breast implants and the development of ALCL.…”

Section: Systematic Review: Anaplastic Large Cell Lymphoma Following ...mentioning

confidence: 99%

Systematic Review: Anaplastic Large Cell Lymphoma Following Breast Implant Surgery

Eveline

Nata’atmadjaa

Lestari

et al. 2023

JRE

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Highlights: BIA-ALCL, a T-cell lymphoma associated with breast implants, is posing a growing medical challenge due to the increasing use of implants for cosmetic and reconstructive purposes The majority of BIA-ALCL cases were associated with cosmetic reasons for breast implants, and textured implants were predominantly implicated. Abstract: Introduction: BIA-ALCL, a T-cell lymphoma associated with breast implants, poses a growing medical challenge despite its relatively low occurrence, due to the increasing use of implants for cosmetic and reconstructive purposes. Our objective is to review the incidence, characteristics of patients, implant types, management, and outcome of BIA-ALCL. Methods: Pubmed and Science Direct databases were searched to identify case series and observational research. A systematic review was conducted by looking up the keywords “breast implant” and “anaplastic large cell lymphoma”. Result: 11 relevant articles were assessed. A total of 353 BIA-ALCL cases have been reported. The mean age at diagnosis was 59.6 years. More than half (53.26%) of the reasons for the breast implants in BIA-ALCL patients were cosmetic. The mean time from breast implant placement to diagnosis was 9.99 years. The majority (71.39%) of documented BIA-ALCL cases have been associated with textured devices. BIA-ALCL patients mainly presented with seroma (54.67%). Outcomes included remission (71%), death because of the disease (4.25%), and recurrence (3.96%) with a mean time of duration of follow-up was 2.53 years. Conclusion: BIA-ALCL is rare cancer in some patients with breast implants but is increasing in incidence largely due to consistent and long-term follow-up. It is important for physicians involved in the care of patients with breast implants to be aware of BIA-ALCL and do routine breast exams.

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Section: Systematic Review: Anaplastic Large Cell Lymphoma Following ...mentioning

confidence: 99%

Systematic Review: Anaplastic Large Cell Lymphoma Following Breast Implant Surgery

Eveline

Nata’atmadjaa

Lestari

et al. 2023

JRE

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“…Proper orientation and marking of the specimen is mandatory to allow for anatomic location of the disease, tumor surveillance and, if indicated, reexcision. Co et al 45 , in a recent systematic review found that a mastectomy had been performed in only 2% of patients (8/395). At present, there is no clear role for mastectomy or sentinel node biopsy 41 .…”

Section: Treatmentmentioning

confidence: 99%

“…A few patients have undergone ablative chemotherapy followed by hematopoietic stem cell transplant. The experience, however, is still limited 5,45,46 .…”

Section: Treatmentmentioning

confidence: 99%

Two critically ill pregnant patients with SARS-CoV-2: A clinical cases report from the Republic of Cyprus

Syka¹,

Alexandrou²,

Palazis³

2021

HJOG

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An interdisciplinary and individualized approach should be implemented with regard to the management of severe COVID-19 in pregnancy. The present study deals with the clinical course of 2 pregnant women who have been diagnosed with this disease and needed admission to an ICU and mechanical respiratory support in Cyprus. The data collection took place in a general ICU of the General Hospital of Nicosia.In certain regions of the world, up to 15% of pregnant women were found to have a positive result on polymerase chain reaction testing for SARS-CoV-2 upon admission for delivery. While pregnant women do not appear to be at substantially higher risk of severe manifestations from COVID-19 compared with non-pregnant adults, the disease has resulted in severe maternal morbidity and mortality in both high- and low-resource settings.

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A Systematic Review of Outcomes Following Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL)

et al. 2022

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Breast Implant-associated Anaplastic Large Cell Lymphoma – a Systematic Review with Pooled Analysis

Cited by 4 publications

References 66 publications

Systematic Review: Anaplastic Large Cell Lymphoma Following Breast Implant Surgery

Systematic Review: Anaplastic Large Cell Lymphoma Following Breast Implant Surgery

Two critically ill pregnant patients with SARS-CoV-2: A clinical cases report from the Republic of Cyprus

A Systematic Review of Outcomes Following Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL)

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