Breast fibroadenomas: a review in the light of current literature

Abstract

<br><b>Introduction:</b> Fibroadenomas are one of the most common benign tumors of the breast in the adolescent females accounting for about 2/3<sup>rd</sup> of all the breast lumps and more than half of all the biopsied breast lesions. They come into being due to overgrowth of glandular tissue under the influence of hormonal changes that the girls undergo at the time of puberty. Due to the wide prevalence of fibroadenomas and the psychosocial morbidity associated with the finding of a breast mass, it is imperative for physicians treating adolescent patients to be thoroughly familiar and updated with this disease. <br><b>Aim:</b> The article aims at providing a brief review of the classification, presentation, diagnosis, and update on the management of breast fibroadenomas on the basis of recent literature.

Rare and unusual occurrence of atypical fibroadenoma on ultrasound

“…Fibroadenoma has a presentation in young women below 30 years and constitutes the most common benign breast tumour in the age group. 1 Mammography and ultrasound are imaging investigations for assessment of breast lesions. However, confirmatory diagnosis of fibroadenoma is based on histopathological examination.…”

Giant Juvenile Fibroadenoma in a 9-Year-Old Girl With Marfan Syndrome

“…While the exact etiology of fibroadenomas is unknown, development of these lesions is likely due to an abnormal hormonal response to exogenous or endogenous estrogen as evidenced by the increase in frequency and size during puberty, pregnancy, and regression after menopause. 2 Our patient was diagnosed with Marfan’s syndrome at the age of 3. Marfan’s syndrome is an autosomal dominant, rare connective tissue disorder that impacts many different organ systems.…”

“…This protective effect increased with longer duration of OC use. 1,2 Perhaps our patient was not taking OCs long enough to experience its protective effects. Interestingly, African American adolescent females, such as our patient, and East Asian females are at the greatest risk of developing GJFs.…”

Imaging of fibroadenoma: Be careful with imaging follow-up

“…Histopathological examination can be performed in the following situations respectively; In the presence of suspicious findings on sonographic examination, an increase in size during sonographic follow-up, an immobile and poorly circumscribed lesion, advanced age (> 35 years), a family history of cancer, and a lesion greater than 2.5 cm in diameter[ 13 - 15 ].…”