Breaking up prolonged sitting with light-intensity walking improves postprandial glycemia, but breaking up sitting with standing does not

Bailey, Daniel; Locke, Christopher D.

doi:10.1016/j.jsams.2014.03.008

Cited by 277 publications

(326 citation statements)

References 26 publications

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“…intensity and frequency of breaks and duration of prolonged sitting (1,9,16,17,30). Importantly, distinct from the majority of experimental studies which have interrupted sitting with short periods of activities (2), the current setup differentiates the independent effects of sitting and standing.…”

Section: A C C E P T E Dmentioning

confidence: 99%

“…Therefore, standing may benefit glucose tolerance through mechanisms linked to either increased carbohydrate or fat oxidation, but these mutually inhibitory mechanisms have not been quantified concurrently with muscle activity and metabolic markers during standing. Concurrent measurement of these potential mechanisms is required to explain why in some studies standing has not elicited metabolic benefits (1,23), and thus to elucidate whether standing is a healthy alternative to sitting.…”

Section: Introductionmentioning

confidence: 99%

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Acute Metabolic Response, Energy Expenditure, and EMG Activity in Sitting and Standing

Gao

Silvennoinen

Pesola

et al. 2017

Medicine &Amp; Science in Sports &Amp; Exercise

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Purpose: While merely standing up interrupts sedentary behavior, it is important to study acute metabolic responses during single bouts of sitting and standing to understand the physiological processes affecting the health of office workers. Methods: 18 healthy middle aged women aged 49.4 ± 7.9 years (range: 40 to 64) with a BMI of 23.4 ± 2.8 kg·m -2 volunteered for this laboratory-based randomized crossover trial where they performed two hours desk work either in sitting or standing postures after overnight fasting. Muscle activity (normalized to walking at 5 km/h), respiratory gas exchange and blood samples were assessed following glucose loading (75 g). Results: Compared with seated work, continuous standing resulted in greater activity in the thigh muscles (mean of biceps femoris and vastus lateralis: 17 ± 8% vs. 7 ± 2%, p < 0.001), and leg muscles (mean of tibialis anterior, gastrocnemius medialis and soleus: 16 ± 6% vs. 7 ± 3%, p<0.001), but no increases in back muscle activity (thoracic erector spinae, lumbar erector spinae and multifidus). Concomitant with ~9% higher energy expenditure (EE) (p = 0.002), standing resulted in higher fat oxidation (48 ± 9%EE vs. 39 ± 7%EE, p = 0.008) and lower carbohydrate oxidation (52 ± 9%EE vs. 61 ± 7%EE, p = 0.008) than sitting. Glucose total and net incremental area under the curve were ~10% (p = 0.026) and ~42% (p = 0.017) higher during standing than sitting, respectively. Insulin concentration did not differ between conditions. Conclusion:Compared to sitting, two hours of standing increased muscle activity, fat oxidation and circulating glucose level. These results suggest fuel switching in favor of fat oxidation during standing despite extra carbohydrate availability.

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Section: A C C E P T E Dmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Acute Metabolic Response, Energy Expenditure, and EMG Activity in Sitting and Standing

Gao

Silvennoinen

Pesola

et al. 2017

Medicine &Amp; Science in Sports &Amp; Exercise

View full text Add to dashboard Cite

show abstract

“…Recently, Bailey and Locke (2014) found that SB breaks every 20 min with 2 min of light intensity walking reduced postprandial plasma glucose concentration (iAUC 18.5 mmol l ). Therefore, physical activity interventions should aim to interrupt SB with a physical activity that is a movement-based LIPA.…”

Section: Sedentary Behaviour and Physical Activity: Impact On Glucosementioning

confidence: 99%

“…Although it is evident that frequent MVPA can protect against the effects of aging on glucose control (Yamanouchi et al 1992), it can be difficult for elderly populations to accumulate the recommended levels of MVPA. Therefore, future intervention studies, similar to the work of Peddie et al (2013), Healy et al (2008a), and Bailey and Locke (2014) should be conducted using aging populations, whose waking hours are predominantly spent performing SB (Harvey et al 2013), to examine the potential benefits of LIPA breaks.…”

Section: Sedentary Behaviour and Physical Activity: Impact On Glucosementioning

confidence: 99%

The emergence of sedentary behaviour physiology and its effects on the cardiometabolic profile in young and older adults

Ryan

Stebbings

Onambélé

2015

AGE

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It has recently emerged that sedentary behaviour is independent of a lack of physical activity as individuals can be sufficiently active, based on the recommended physical activity guidelines, but also spend the majority of their waking hours engaging in sedentary behaviour. Individuals who follow this pattern of physical activity and sedentary behaviour are known as 'active couch potatoes'. Sedentary behaviour has been found to have detrimental effects on cardiometabolic markers associated with cardiovascular disease. Since the positive effects of moderate-to-vigorous intensity physical activity do not necessarily negate the deleterious effects of sedentary behaviour on cardiometabolic markers, it is postulated that engaging in light physical activity is an intervention that will successfully reduce levels of sedentary behaviour and may hence improve health markers of quality of life. We propose that such lifestyle changes may be particularly relevant to older populations as these engage in sedentary behaviour for the majority of their waking hours, thereby adding to the negative aging effect on cardiometabolic markers.

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“…Recent studies utilizing a similar intermittent walking approach throughout the day have also shown improvements in glucose control (Bailey & Locke, 2014;Dunstan et al, 2012;Francois et al, 2014;Peddie et al, 2013). Francois et al (2014) recently investigated the impact of small doses of high-intensity walking (exercise snacks) on blood glucose control in nine individuals with IFG.…”

Section: Walking and Postprandial Hyperglycemiamentioning

confidence: 99%

Effects of Postmeal Walking on Postprandial Glucose Control and Oxidative Stress

Knurick

Johnston

2016

Medicine & Science in Sports & Exercise

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Background: Postprandial hyperglycemia can increase levels of oxidative stress and is an independent risk factor for complications associated with type 2 diabetes. Purpose:To evaluate the acute effects of a 15-min postmeal walk on glucose control and markers of oxidative stress following a high-carbohydrate meal.Methods: Ten obese subjects (55.0 ± 10.0 yrs) with impaired fasting glucose (107.1 ± 9.0 mg/dL) participated in this repeated measures trial. Subjects arrived at the laboratory following an overnight fast and underwent one of three conditions: 1) Test meal with no walking or fiber (CON), 2) Test meal with 10g fiber and no walking (FIB), 3) Test meal with no fiber followed by a 15-min treadmill walk at preferred walking speed (WALK).Blood samples were taken over four hours and assayed for glucose, insulin, thiobarbituric reactive substances (TBARS), catalase, uric acid, and total antioxidant capacity (TAC). A iii ACKNOWLEDGEMENTS

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Breaking up prolonged sitting with light-intensity walking improves postprandial glycemia, but breaking up sitting with standing does not

Cited by 277 publications

References 26 publications

Acute Metabolic Response, Energy Expenditure, and EMG Activity in Sitting and Standing

Acute Metabolic Response, Energy Expenditure, and EMG Activity in Sitting and Standing

The emergence of sedentary behaviour physiology and its effects on the cardiometabolic profile in young and older adults

Effects of Postmeal Walking on Postprandial Glucose Control and Oxidative Stress

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