Brazilian Bromeliaceae species: isolation of arylpropanoid acid derivatives and antiradical potential

Rocha, Fabíola D.; Yano, M; Cunha, Márcio R. da; Gabriel, Felipe T.; Cordeiro, Renato S.B.; Menezes, Fábio S.; Kaplan, Maria Auxiliadora Coelho

doi:10.1590/s0102-695x2010000200017

Cited by 5 publications

(3 citation statements)

References 25 publications

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“…The NMR (in (D 6 )DMSO) data were similar to those (in C 5 D 5 N and CD 3 OD) reported in [12] [13] because different solvents were used for NMR experiments [13]. …”

Section: Resultssupporting

confidence: 69%

Phenolic Derivatives from the Root Bark of Oplopanax horridus

Huang

Zhang

Wang

et al. 2015

Helvetica Chimica Acta

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Four new phenolic derivatives, including two phenylpropanoid glycosides, one benzoate glycoside, and one lignan glycoside, together with one known glyceride, were isolated from the root bark of Oplopanax horridus. The structures of the new compounds were elucidated as 3-{4-[(6-O-acetyl-β-D-glucopyranosyl) oxy]-3,5-dimethoxyphenylpropanoic acid (1), (+)-[5,6,7,8-tetrahydro-7- (hydroxylmethyl)-10,11-dimehoxydibenzo[a,c][8]annulen-6-yl]methyl β-D-glucopyranoside (2), (+)-methyl 4-[6-O-{3-hydroxy-3-methyl-5-(1-methylpropyl)oxy]-5-oxopentanoyl}-4-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl)oxy]-3-methoxybenzoate (3), and 2-methoxy-4-[(1E)-3-methoxy-3-oxoprop-1-en-1-yl]phenyl 6-O-{3-hydroxy-3-methyl-5-[(1-methylpropyl)oxy]-5-oxopentanoyl-4-O-β-D-glucopyranosyl-β-D-glucopyranoside (4) on the basis of spectroscopic techniques including NMR and MS analyses. The known compound was identified as glycer-2-yl ferulate (5) by comparing its physical and spectral data with those reported in the literature.

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“…The NMR (in (D 6 )DMSO) data were similar to those (in C 5 D 5 N and CD 3 OD) reported in [12] [13] because different solvents were used for NMR experiments [13]. …”

Section: Resultssupporting

confidence: 69%

Phenolic Derivatives from the Root Bark of Oplopanax horridus

Huang

Zhang

Wang

et al. 2015

Helvetica Chimica Acta

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“…De acordo com Machado et al (2008), os flavonoides atuam como doadores de elétrons de forma a apresentarem ação neutralizadora de radicais livres durante o processo oxidativo. Desta forma, a presença de flavonoides nas amostras analisadas está diretamente relacionada com a existência de atividade antioxidante (ROCHA et al, 2010). Antropova (2019) correlaciona as atividades antirradicais e anticâncer de espécies vegetais com a presença de cumarinas.…”

Section: Resultados E Discussõesunclassified

Quantificação do potencial antioxidante de plantas medicinais comercializadas em porto velho/RO

Batista¹,

Silva²,

Ramos³

2022

BJDV

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Avaliar a capacidade antioxidante das plantas Sucuúba (Himatanthus sucuuba (Spruce ex Müll. Arg.) Woodson), Jaborandi (Pilocarpus microphyllus Stapf ex Wardleworth), Carapanaúba (Aspidosperma nitidum Benth. ex Müll. Arg.), Pariparoba (Pothomorphe umbellata), Guiné (Petiveria alliacea), Quebra pedra (Phyllanthus niruri), Casca D’anta (Drimys brasiliensis Miers), Bugre (Rudgea viburnoides (Charm.) Benth) com identificação dos principais metabólitos secundários encontrados em plantas. Foram preparados extratos acetato de etila, etanólicos e metanólicos das folhas, cascas e flores da Sucuúba, Jaborandi, Carapanaúba, Pariparoba, Guiné, Quebra-pedra, Casca D’anta e Bugre adquiridas em ervarias do município de Porto Velho/RO. Cada extrato foi inicialmente submetido à prospecção dos metabólitos secundários e posteriormente as diluições de 250, 500 e 750 µg.ml-1 foram analisadas o potencial antioxidante pelo método de sequestro do radical DPPH (2,2-difenil-1-picril-hidrazil). Nos experimentos, as amostras apresentaram resultado positivo para todos os metabólitos secundários analisados, diferenciando apenas quanto ao tipo de solvente utilizado devido a incompatibilidade do solvente com o composto que se desejou identificar. Em relação a atividade antioxidante, as amostras demonstraram divergência na capacidade sequestradora do radical DPPH variando de 24,92% (guiné) a 86,28% (quebra-pedra). Diante dos resultados apresentados todas as amostras apresentaram capacidade antioxidante frente o radical DPPH e essa atividade foi associada às classes químicas identificadas inicialmente, sendo elas: triterpenos, flavonoides, taninos, cumarinas, alcaloides e saponinas. A diferença nos percentuais do potencial antioxidante foi correlacionada a quantidade de metabólito secundário presentes nas plantas bem como habitat e período de colheita das amostras que interferem diretamente nos resultados.

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“…The family Bromeliaceae fascinates by the exuberance, diversity and beauty of its species (Rocha et al, 2010). Neoglaziovia variegata is a species native to the lower stratum of the Brazilian Caatinga.…”

Section: Introductionmentioning

confidence: 99%

Antinociceptive effect of the ethanolic extract of Neoglaziovia variegata (Bromeliaceae) in mice

Sarah¹,

Henrique²,

Juliane³

et al. 2012

J. Med. Plants Res.

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This study was carried out to evaluate the antinociceptive effects of ethanolic extract from Neoglaziovia variegata (Nv-EtOH) in mice using models of nociception. The evaluation of antinociceptive activity was carried out by the acetic acid-induced writhing, formalin and hot plate tests. HPLC was used to determine the fingerprint chromatogram of the Nv-EtOH. In the acetic acid-induced writhing test, the Nv-EtOH (100, 200 and 400 mg/kg, i.p.) reduced the number of writhing by 89.50, 71.34 and 87.42%, respectively. Additionally, the extract decreased by 46.67, 44.23 and 41.81%, respectively, the paw licking time in the first phase of the formalin test, as well as 70.14, 69.43 and 90.28%, respectively, in the second phase of this test. In the hot plate test, Nv-EtOH increased the reaction time when compared to control group. The effects of Nv-EtOH and morphine in the formalin and hot plate tests were antagonized by naloxone. The presence of phenolic compounds in the extract was confirmed using HPLC. Results based from formalin and hot plate tests indicated that the extract has compounds that interact with the opioid system. The effect of Nv-EtOH on hot plate response provides a confirmation of its central effect. Pharmacological and chemical studies are continuing in order to characterize the mechanism responsible for this effect.

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Brazilian Bromeliaceae species: isolation of arylpropanoid acid derivatives and antiradical potential

Cited by 5 publications

References 25 publications

Phenolic Derivatives from the Root Bark of Oplopanax horridus

Phenolic Derivatives from the Root Bark of Oplopanax horridus

Quantificação do potencial antioxidante de plantas medicinais comercializadas em porto velho/RO

Antinociceptive effect of the ethanolic extract of Neoglaziovia variegata (Bromeliaceae) in mice

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