“…Parametric studies have demonstrated that brainskull boundary conditions over the cerebrum in FE models can strongly influence model predictions of local mechanical responses (Al-Bsharat et al, 1999;Bandak and Eppinger, 1994;Chu et al, 1994;DiMasi et al, 1991DiMasi et al, , 1995Lighthall et al, 1989;Miller et al, 1998;Ruan et al, 1994;Takhounts et al, 2003;Ueno et al, 1989Ueno et al, , 1995Zhang et al, 2001), but limited experimental data are available for validation. With no consensus, the brain-skull interface has been represented as tied (no brain-skull relative slip) or sliding (with or without friction, with or without brain-skull separation).…”