Brain natriuretic peptide (BNP) testing in the emergency department

Mayo, Douglas; Colletti, James E.; Kuo, Dick

doi:10.1016/j.jemermed.2005.08.022

Cited by 14 publications

(11 citation statements)

References 78 publications

(61 reference statements)

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“…BNP can also be elevated in patients with pulmonary embolism, renal failure, shock, lung disease with right‐sided heart failure, and myocardial infarction 23 . The large majority of patients in both the control and the case groups were oncology patients.…”

Section: Discussionmentioning

confidence: 99%

N‐terminal pro‐brain natriuretic peptide is a useful diagnostic marker for transfusion‐associated circulatory overload

et al. 2008

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Section: Discussionmentioning

confidence: 99%

N‐terminal pro‐brain natriuretic peptide is a useful diagnostic marker for transfusion‐associated circulatory overload

et al. 2008

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“…BNP was detected by a double-antibody sandwich immunoenzyme method, using Unicel-TM-DXI800 (Beckman, CA, USA) full-automated immunoassay instrument. The ELISA was performed, as described previously [32].…”

Section: Detection Of Brain Natriuretic Peptide (Bnp) By Elisamentioning

confidence: 99%

The plasma level of mCRP is linked to cardiovascular disease in antineutrophil cytoplasmic antibody-associated vasculitis

Liang

Huang

et al. 2020

Arthritis Res Ther

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Background C-reactive protein (CRP) has two natural isomers: C-reactive protein pentamer (pCRP) and C-reactive protein monomer (mCRP). The levels of CRP are significantly elevated in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). mCRP not only activates the endothelial cells, platelets, leukocytes, and complements, but also has a proinflammatory structural subtype that can localize and deposit in inflammatory tissues. Thus, it regulates a variety of clinical diseases, such as ischemia/reperfusion (I/R) injury, Alzheimer’s disease, age-related macular degeneration, and cardiovascular disease. We hypothesized that plasma mCRP levels are related to cardiovascular disease in AAV. Methods In this cross-sectional study, 37 patients with AAV were assessed. Brain natriuretic peptide (BNP) and mCRP in plasma were assessed by enzyme-linked immunosorbent assay (ELISA). The acute ST-segment elevation myocardial infarction (STEMI) was diagnosed by coronary angiography, and the Gensini score calculated. Echocardiography evaluated the ejection fraction (EF%), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), and left ventricular mass index (LVMI). Estimated glomerular filtration rate (eGFR) was calculated based on serum creatinine, age, and gender. Results The plasma level of mCRP in AAV was significantly higher than that in healthy volunteers (P < 0.001). Then, mCRP and CRP levels were compared with and without STEMI complications in AAV. The plasma level of mCRP was higher, but that of CRP was lower in STEMI. The plasma level of mCRP was correlated with Birmingham vasculitis activity score (BVAS), eGFR, BNP, EF%, LVEDV, LVESV, LVMI, and STEMI complications’ Gensini score in AAV; however, CRP did not correlate with BNP, EF%, LVEDV, LVESV, LVMI, and Gensini score. Conclusions The plasma level of mCRP was related to cardiovascular diseases in AAV patients.

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“…POC tests for BNP and the amino-terminal co-metabolite (NT-proBNP) have often been used to assist in the determination of underlying cause (Clerico et al, 2012, Mayo et al, 2006). For emergency care patients, this test should be performed within one hour of blood collection (Carpenter et al, 2012).…”

Section: Emergency Departmentmentioning

confidence: 99%

Point-of-care diagnostics for niche applications

Cummins

Ligler

Walker

2016

Biotechnology Advances

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Point-of-care or point-of-use diagnostics are analytical devices that provide clinically relevant information without the need for a core clinical laboratory. In this review we define point-of-care diagnostics as portable versions of assays performed in a traditional clinical chemistry laboratory. This review discusses five areas relevant to human and animal health where increased attention could produce significant impact: veterinary medicine, space travel, sports medicine, emergency medicine, and operating room efficiency. For each of these areas, clinical need, available commercial products, and ongoing research into new devices are highlighted.

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Brain natriuretic peptide (BNP) testing in the emergency department

Cited by 14 publications

References 78 publications

N‐terminal pro‐brain natriuretic peptide is a useful diagnostic marker for transfusion‐associated circulatory overload

N‐terminal pro‐brain natriuretic peptide is a useful diagnostic marker for transfusion‐associated circulatory overload

The plasma level of mCRP is linked to cardiovascular disease in antineutrophil cytoplasmic antibody-associated vasculitis

Point-of-care diagnostics for niche applications

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