Brain metabolite rates in amygdala and hippocampus in vaginismus patients

Erbay, Mehmet Fatih; Zayman, Esra Porgalı

doi:10.5455/medscience.2020.09.9222

Cited by 1 publication

(1 citation statement)

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“…By triggering the release of neurotransmitters like dopamine, and hormones such as oxytocin and endorphins, NPSA creates a neurochemical environment that is associated with pleasure, bonding and relaxation. 29 This chemical response not only counters depressive symptoms but also induces neural plasticity, reconditioning neural responses to sexual intimacy. Additionally, NPSA reduces stress, regulates cortisol levels and fosters positive neurofeedback, enhancing self-efficacy and self-esteem.…”

Section: Discussionmentioning

confidence: 99%

Association between non-penetrative sexual activities and depression in women with vaginismus: a cross-sectional study

Yavuzkir,

Aslan,

Yurt

et al. 2024

J Int Med Res

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Objective This cross-sectional study aimed to explore the association between non-penetrative sexual activities (NPSA) and depression levels in women diagnosed with vaginismus. Methods A cross-sectional retrospective study was conducted between March 2016 and June 2019, after approval by the Fırat University Faculty of Medicine ethics committee. Participants comprised married women referred to our female sexual dysfunction outpatient clinic with vaginismus. Diagnosis of vaginismus was established following comprehensive evaluations, including gynecological examination and psychiatric assessment. Sociodemographic data and Beck Depression Inventory (BDI) scores were collected. We compared depression levels between women who engaged in NPSA and those who did not. Results Of the 75 women with primary vaginismus included in the study, 18 did not engage in any NPSA and 57 engaged in at least one NPSA. The average BDI score of those who engaged in NPSA was significantly lower than those who did not. A negative correlation was found between the number of NPSA engaged in and BDI scores (r = −0.494). Conclusions Women with vaginismus had high depression scores, but engaging in NPSA was associated with lower depression levels. The findings suggest that incorporating NPSA into clinical interventions may be beneficial for managing depression in women with vaginismus.

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Section: Discussionmentioning

confidence: 99%