Brain Lesions in Cerebral Venous Sinus Thrombosis

Zubkov, Alexander Y.; McBane, Robert D.; Brown, Robert D.; Rabinstein, Alejandro A.

doi:10.1161/strokeaha.108.529172

Cited by 43 publications

(42 citation statements)

References 6 publications

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“…Advances in diffusion- and perfusion-weighted MR have contributed to improve the understanding of brain lesions associated with venous occlusion [2,3,4,13,14,15]. MRI has demonstrated the coexistence of both cytotoxic and vasogenic edema [4,8,14,16] in patients with CVT.…”

Section: Discussionmentioning

confidence: 99%

Cerebral Venous Thrombosis with Nonhemorrhagic Lesions: Clinical Correlates and Prognosis

et al. 2010

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Background and Purpose: Brain imaging of patients with acute cerebral venous thrombosis often shows parenchymal hemorrhagic and nonhemorrhagic lesions. The clinical relevance of nonhemorrhagic lesions is poorly known. Method: In the International Study on Cerebral Vein and Dural Sinus Thrombosis cohort, demographic, clinical, risk factor, prognosis and imaging findings were compared between patients with parenchymal nonhemorrhagic lesions and no hemorrhagic lesions (NHL) and (1) patients with parenchymal hemorrhagic lesions (HL) and (2) patients without brain lesions. Predictors of prognosis at the end of follow-up in the NHL group were analyzed by bivariate and Cox regression methods. Results: We identified 147 patients (23.6%) with NHL. When compared to patients without brain lesions (n = 309), those with NHL more often presented mental status disturbances, aphasia, decreased alertness, motor deficits, seizures, occlusions of the straight sinus, deep venous system and cortical veins. Patients with NHL had a better prognosis in the acute phase and at the end of follow-up than those with HL, but a worse one than patients without brain lesions, as more NHL patients were dead or dependent (modified Rankin Scale score = 3–6) at discharge (19.7 vs. 6.5%, p < 0.001) and final follow-up (14.3 vs. 7.4%, p = 0.03). In Cox regression analysis, coma (HR = 13.7; 95% CI = 4.3–43.7) and thrombosis of the deep venous system (HR = 3.5; 95% CI = 1.4–8.7) were associated with death or dependency at the end of follow-up. Conclusion: Cerebral venous thrombosis patients with NHL are intermediate between patients without brain lesions and those with HL, both in initial clinical picture and prognosis.

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Section: Discussionmentioning

confidence: 99%

Cerebral Venous Thrombosis with Nonhemorrhagic Lesions: Clinical Correlates and Prognosis

et al. 2010

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“…Bazı hastalarda sadece hafif semptomlara yol açarken, bazı hastalarda ise hemorajik venöz infarkt ve şiddetli intrakraniyal hipertansiyon gibi ciddi komplikasyonlara da neden olabilmektedir (2). SVT'nin semptom ve bulguları, iki farklı mekanizmayla ortaya çıkmaktadır.…”

Section: Introductionunclassified

“…Kötü prognoz faktörleri, ileri yaş, koma, kortikal ve derin serebral venöz sistemin tutulumu, artmış intrakraniyal basınç, SVT'nin maligniteye sekonder oluşması, parankim tutulumunun olması (ödem, hemoraji), kontrol altına alınmayan epileptik nöbetler ve pulmoner emboli gibi komplikasyonların olmasıdır (2,3,5).…”

Section: Introductionunclassified

The prognostic value of increased leukocyte and neutrophil counts in the early phase of cerebral venous sinus thrombosis

Kamışlı¹,

Kamışlı²,

Gönüllü³

et al. 2012

Türk Beyin Damar Hast Derg

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“…The spectrum of clinical presentations in patients with cerebral venous sinus thrombosis (CVST) varies considerably [1]. While some patients with CVST have relatively mild symptoms, others develop devastating complications, including hemorrhagic venous infarctions and severe intracranial hypertension [1].…”

Section: Introductionmentioning

confidence: 99%

“…While some patients with CVST have relatively mild symptoms, others develop devastating complications, including hemorrhagic venous infarctions and severe intracranial hypertension [1]. …”

Section: Introductionmentioning

confidence: 99%

Venous Stasis and Cerebrovascular Complications in Cerebral Venous Sinus Thrombosis

et al. 2017

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Background/Aims: The factors related to cerebrovascular complications in cerebral venous sinus thrombosis (CVST) are controversial. We focused on venous stasis and investigated its relationship with cerebrovascular complications in CVST. Methods: CVST patients between June 2013 and October 2016 were enrolled. Relationships between cerebrovascular complications, defined as cerebral venous infarction, intracerebral hemorrhage, or subarachnoid hemorrhage, and cerebrum venous stasis and other clinical information were retrospectively analyzed. Venous stasis was evaluated by the prominence of the veins on susceptibility-weighted imaging (SWI). The cerebrum was divided into 10 regions according to the venous drainage territories, and venous stasis was quantified by adding one point for venous prominence on SWI for each region (CVST SWI score). Results: All 5 cases in the noncomplicated group had a CVST SWI score of 0. The 3 patients with CVST SWI scores higher than 0 had cerebrovascular complications. The CVST SWI scores were higher in the complicated group than in the noncomplicated group (3.0 vs. 0, p = 0.010). Seizures were seen in all patients with complications and in none of the patients without complications (3 vs. 0, p = 0.018). Conclusion: Venous stasis evaluated by SWI can help predict cerebrovascular complications in CVST. A seizure is an important initial symptom that suggests cerebrovascular complications in CVST.

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Brain Lesions in Cerebral Venous Sinus Thrombosis

Cited by 43 publications

References 6 publications

Cerebral Venous Thrombosis with Nonhemorrhagic Lesions: Clinical Correlates and Prognosis

Cerebral Venous Thrombosis with Nonhemorrhagic Lesions: Clinical Correlates and Prognosis

The prognostic value of increased leukocyte and neutrophil counts in the early phase of cerebral venous sinus thrombosis

Venous Stasis and Cerebrovascular Complications in Cerebral Venous Sinus Thrombosis

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