Brain Ischemia Instantaneously Tracked by the Narcotrend EEG Device

Rinösl, Harald; Fleck, Tatjana; Dworschak, Martin

doi:10.1053/j.jvca.2012.10.008

Cited by 4 publications

(4 citation statements)

References 5 publications

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“…However, the advantage of the NI scale is that it can monitor the changes of consciousness level of patients during anesthesia in real time (18,19). In the present study, we found that in groups B and C, NIs were significantly decreased at T2-6, the Ramsay scores were increased at T3-6, and the differences were statistically significant (P<0.05).…”

Section: Discussionmentioning

confidence: 99%

Assessment of different loading doses of dexmedetomidine hydrochloride in preventing adverse reaction after combined spinal-epidural anesthesia

Jiang

Wang

et al. 2017

Experimental and Therapeutic Medicine

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We conducted the present study to investigate the effects of the different loading doses of dexmedetomidine hydrochloride in the prevention of adverse reactions after combined spinal-epidural anesthesia. A total of 200 patients that were admitted to the Department of Obstetrics at the Second Affiliated Hospital of Xi'an Jiaotong University hospital and treated with cesarean section through the use of combined spinal-epidural anesthesia from December, 2014 to June, 2016, were randomly divided into 4 groups. The therapeutic regimens of patients were shown as follows: group A was administered an intravenous pump of 10 ml/l physiological saline in surgery until the end of the delivery. group B was administered 0.2 µg/kg dexmedetomidine. group C was administered 0.4 µg/kg dexmedetomidine. group D was administered 0.6 µg/kg dexmedetomidine. The anesthesia plane was adjusted to the level below the T10 plane. After the onset of anesthesia, participants of each group were treated with an intravenous pump of dexmedetomidine at loading dose. After intravenous pumping for 10 min in each group during the surgery, patients were administered with an intraoperative maintenance dose of 0.2 µg/kg/h until the end of the delivery. The heart rate (HR), mean arterial pressure (MAP), Narcotrend index (NI), Ramsay sedation score and the incidence of adverse reactions at each time-point of the start of drug administration (T0), 10 min (T2), 30 min (T3), 60 min (T4), 90 min (T5) and the end of surgery (T6) were recorded. Within 24 h post-delivery, the degree of amnesia from using dexmedetomidine until the end of the delivery were followed up. Compared to group A and T0, the HRs of participants at T3-6 in groups B and C were decreased. The MAP at T1 in group D was increased. In groups B and C, the NIs were significantly decreased at T2-6, the Ramsay scores were increased at T3-6, and the differences were statistically significant (P<0.05). The follow-up within 24 h after delivery showed that the degree of anterograde amnesia from groups B to D was significantly higher than group A, with statistically significant difference (P<0.05). A combined spinal-epidural anesthesia with 0.6 µg/kg loading dose of dexmedetomidine, by intravenous pumping within 10 min before cesarean section, can achieve a satisfied sedative effect at 30 min after administration. It maintains the characteristics of intraoperative hemodynamic stability and less adverse reactions. Therefore, it is of great significance to improve the quality of cesarean section delivery.

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Section: Discussionmentioning

confidence: 99%

Assessment of different loading doses of dexmedetomidine hydrochloride in preventing adverse reaction after combined spinal-epidural anesthesia

Jiang

Wang

et al. 2017

Experimental and Therapeutic Medicine

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“…This systematic review has certain limitations that should be noted. At present, there are few studies on Narcotrend monitoring the influence of different depths of anesthesia on POCD in China and abroad (36). Due to the high literature requirements for meta-analysis, only eight articles met the final inclusion criteria.…”

Section: Discussionmentioning

confidence: 99%

Systematic review and meta-analysis of the prognostic value of Narcotrend monitoring of different depths of anesthesia and different Bispectral Index (BIS) values for cognitive dysfunction after tumor surgery in elderly patients

Shi¹,

Chen²,

Ni³

et al. 2022

Ann Transl Med

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Background: To study the effect of Narcotrend monitoring on the incidence of early postoperative cognitive dysfunction (POCD) under different Bispectral Index (BIS) conditions and the effect of different depths of anesthesia on the incidence of POCD. Methods:We performed a literature search of the PubMed, Embase, OVID (database system made by Ovid Technologies, USA), Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), VIP Chinese Sci-tech Journals Database, Wanfang Data, etc. from the date of establishment of the database until December 31, 2020.Results: In the end, eighty articles were included, with a total of 714 patients. The meta-analysis results showed that four articles (255 patients) compared the state of deep anesthesia (BIS 30-40) with conventional anesthesia (BIS 40-60 earlier) after POCD. Also, the incidence of POCD on the first day after deep anesthesia [Narcotrend stage (NTS): negative correlation is currently the most appropriate egg description; Nd can subdivide the original electroencephalogram (EEG) into six stages 15 levels (Nd Sg, NTS), or A (state of wakefulness), state B0-B2 (sedated state), state C0-C2 (light anesthetic state), state D0-D2 (general anesthesia), state E0-E2 (deep anesthesia state), and state F0-F2 (burst suppression state)] was significantly lower than that of conventional anesthesia (NTS D0-D1) [odds ratio (OR) =0.21, 95% confidence interval (CI): 0.13-0.35, P<0.00001]. Moreover, the incidence of POCD in deep anesthesia (NTS E1) at 7 days after surgery was significantly lower than that of conventional anesthesia (NTS D0) (OR =0.45, 95% CI: 0.23-0.91, P=0.03), while the incidence of POCD 7 days after NTS D2 in conventional anesthesia was significantly lower than that of NTS D0 (OR =0.42, 95% CI: 0.24-0.71, P=0.001).Discussions: POCDs are thought to be the result of a combination of physical defects and precipitating factors in patients with their own physical impairments, and despite potential adverse effects, there is currently no consensus on the incidence of POCDs in patients with tumor, current risk factors, causes, and prevention strategies. Moreover, the level of evidence is low, and the deviation between different studies cannot be ruled out.

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“…Narcotrend can subdivide the original EEG into six stages and 15 levels (NTS), namely, A (awake state), B0-B2 (sedation state), C0-C2 (light anesthesia state), D0-D2 (conventional anesthesia state), E0-E2 (deep anesthesia state), and F0-F2 (burst suppression state), and use the 0-100 dimensionless anesthesia depth index (Narcotrend index (NI)) to reflect the whole process from awake to deep anesthesia. Compared with BIS, Narcotrend not only distinguishes the state of consciousness over a large span but also provides the advantage of monitoring sudden changes in the depth of anesthesia [24,25].…”

Section: Discussionmentioning

confidence: 99%

Meta-Analysis of the Prognostic Value of Narcotrend Monitoring of Different Depths of Anesthesia and Different Bispectral Index (BIS) Values for Cognitive Dysfunction after Tumor Surgery in Elderly Patients

Chen

2022

Journal of Healthcare Engineering

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Objective. To study the effect of Narcotrend monitoring on the incidence of early postoperative cognitive dysfunction (POCD) under different bispectral index (BIS) conditions and the effect of different depths of anesthesia on the incidence of POCD. Methods. We performed a literature search of PubMed, Embase, OVID (database system made by Ovid Technologies, USA), CBM (Chinese Biomedical Literature database), CNKI (China National Knowledge Infrastructure), Wanfang, and VIP databases (full-text database of Chinese sci-tech journals), etc., from the date of the establishment of the database until December 31, 2020. Our meta-analysis was focused on the collection and study of Narcotrend monitoring of different depths of anesthesia. We carefully read the abstracts and full texts of randomized controlled trials on the incidence of POCD in the early postoperative period, and their references were tracked. Data extraction and quality evaluation of the included literature were also performed, and RevMan 5.3 software was used for analysis. Results. In the end, eight articles were included, with a total of 714 patients. The meta-analysis results showed that four articles (255 patients) compared the state of deep anesthesia (BIS 30–40) with conventional anesthesia (BIS 40–60 earlier) after POCD. Also, the incidence of POCD on the first day after deep anesthesia (Narcotrend stage (NTS): negative correlation is currently the most appropriate EEG description; Nd can subdivide the original EEG into six stages and 15 levels (Nd Sg, NTS), namely, A (state of wakefulness) state, B0 B2 (sedated state), C0 C2 (light anesthetic state), D0 D2 (general anesthesia), and E0–E1) was significantly lower than that of conventional anesthesia (NTS DO–D1) (odds ratio (OR) = 0.21, 95% confidence interval (CI): 0.13–0.35, P < 0.00001 ). Moreover, the incidence of POCD in deep anesthesia (NTS E1) at 7 days after surgery was significantly lower than that of conventional anesthesia (NTS D0) (OR (odds ratio) = 0.45, 95% CI: 0.23–0.91, P = 0.03 ), while the incidence of POCD 7 days after NTS D2 in conventional anesthesia was significantly lower than that of NTS D0 (OR = 0.42, 95% CI: 0.24–0.71, P = 0.001 ). Discussion. Deep anesthesia can reduce the incidence of POCD (OR = 0.40, 95% CI: 0.22–0.73, P = 0.002 ). This meta-analysis included three studies (216 patients) that compared the early postoperative POCD incidence of BIS 40–50 under conventional anesthesia and BIS 50–60; the BIS 40–50 did not significantly reduce the incidence of POCD (OR = 1.11, 95% CI: 0.24–5.24, P = 0.9 ). The incidence of POCD under deep anesthesia with Narcotrend monitoring was lower than that under conventional anesthesia.

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Brain Ischemia Instantaneously Tracked by the Narcotrend EEG Device

Cited by 4 publications

References 5 publications

Assessment of different loading doses of dexmedetomidine hydrochloride in preventing adverse reaction after combined spinal-epidural anesthesia

Assessment of different loading doses of dexmedetomidine hydrochloride in preventing adverse reaction after combined spinal-epidural anesthesia

Systematic review and meta-analysis of the prognostic value of Narcotrend monitoring of different depths of anesthesia and different Bispectral Index (BIS) values for cognitive dysfunction after tumor surgery in elderly patients

Meta-Analysis of the Prognostic Value of Narcotrend Monitoring of Different Depths of Anesthesia and Different Bispectral Index (BIS) Values for Cognitive Dysfunction after Tumor Surgery in Elderly Patients

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