Brain auditory evoked potentials in children with Down syndrome

Caracterização eletrofisiológica da audição em indivíduos com Síndrome de Down

“…In the qualitative analysis, according to Table 2, statistically significant differences were found between the groups in relation to the early classification for the values of absolute latencies of waves I, III, and V. Thus it was possible to observe that 58.82% of the individuals with DS presented early latency for the wave I, 70.58% for the wave III, and 82.35% for the wave V. These results agree with those of other studies that found reduced absolute latency values for the BAEP waves in individuals with DS compared with individuals with typical development (15,(25)(26)(27) . It was also possible to observe higher standard deviation values in the data of the DSC, thus demonstrating greater variability of responses in these individuals compared with those of the control group.…”

“…A study using BAEP conducted with individuals with DS found reduced values of absolute latency for waves I, III, and V in children with or without hearing loss, including conductive hearing loss (14) . Nevertheless, other authors observed reduced latency values for waves I and III and the interpeak I-III only in children aged 18 months or less (15) . Thus it seems to be no consensus on this decrease in latency values.…”

“…It is believed that the age range involved in this study may have interfered with this outcome. Some authors have verified early latency values in the BAEP only for children younger than 18 months, justified by maturational aspects, that is, with maturational development, responses to the BAEP of children with DS tend to resemble those of children with typical development (15,(25)(26)(27) . These early responses are extremely important for the proper analysis and interpretation of the BAEP in children with DS, mainly due to the middle ear changes frequently present in this population, which instead of causing late latency of the waves (a result often found in patients with conductive hearing loss), could lead to latency values within normal range.…”

“…Thus it seems to be no consensus on this decrease in latency values. One of the justifications for these decreased values would be the smaller head circumference of the child with DS, reducing the distance of the transmission of the nervous stimulus (16) ; another would be the higher transmission velocity because of early myelination for the age (15) . Therefore, the aim of the present study was to verify whether the reduced latency values previously described can also be observed in older children or adolescents.…”

Audiological findings in a group of neurologically compromised children: A retrospective study

“…[20] The ABR of children with DS has been shown to present with shorter latencies and lower amplitudes. [21] In severe perinatal asphyxia, amplitudes of all waves -particularly wave V -were reduced in the first month of life. [22] In a study in children with hydrocephalus, 88% of the cohort displayed a wide range of abnormalities on ABR.…”