Bowel Wall Thickness at Abdominal Ultrasound and the One-Year-Risk of Surgery in Patients with Crohn's Disease

Castiglione, Fabiana; Sio, Ilario de; Cozzolino, Andrea; Rispo, Antonio; Manguso, Francesco; Blanco, Giovanna Del Vecchio; Girolamo, Elena Di; Castellano, Luigi; Ciacci, Carolina; Mazzacca, G

doi:10.1111/j.1572-0241.2004.40267.x

Cited by 65 publications

(38 citation statements)

References 25 publications

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“…Moreover, the severity of US findings, particularly a significant increase in transmural thickness, can be a good predictor for the necessity of a surgical intervention [82,86]. US can be considered a surrogate investigation of endoscopy for the assessment of mucosal healing after biological therapy initiation [87].…”

Section: Monitoringmentioning

confidence: 99%

The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

Marin

Tribus

Fierbinţeanu-Braticevici

2018

Med Ultrason

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Inflammatory bowel diseases have an important impact upon the economic and social status due to their increasing incidence and prevalence, often affecting young people. At the moment, the therapeutic goal goes beyond the improvement of symptoms and laboratory parameters, being represented by endoscopic mucosal healing, changing the disease’s natural history. Even though endoscopy is the gold standard for the assessment of mucosal healing, it is an invasive maneuver and it lacks good repeatability. These patients require frequent evaluation; therefore, interest for noninvasive techniques has risen.As a consequence, the importance of intestinal ultrasound has increased lately and recent studies support its use to assess the degree of inflammation, to differentiate between remission and relapse, to monitor therapy response and guide treatment, to evaluate prognosis, and to diagnose complications. Another promising noninvasive imagistic technique is elastography which has gained interest because of its capacity to discriminate between inflammatory and fibrotic tissue, taking into account the different therapeutic options for the fibrotic strictures compared to inflammatory processes. This review summarizes the actual recommendations regarding the use of intestinal ultrasound and elastographic techniques for the diagnosis and monitoring of inflammatory bowel diseases.

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Section: Monitoringmentioning

confidence: 99%

The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

Marin

Tribus

Fierbinţeanu-Braticevici

2018

Med Ultrason

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“…The placement of the nasojejunal tube, necessary for the enteroclysis, is invasive, requires the use of ionizing of patients with CD [39,40] . and in early identifying intraabdominal complications, such as abscesses, fistulae and strictures [41][42][43][44] . The reported sensitivity of US in detecting CD strictures approximately is 74%-80% [41] .…”

Section: Cross Sectional Imagingmentioning

confidence: 99%

Imaging of the small bowel: Crohn’s disease in paediatric patients

Casciani

Vincentiis

Polettini

et al. 2014

WJR

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In more than 20% of all patients, the Crohn's disease presents before the age of 18 years. The diagnosis and management of Crohn's disease in children has changed dramatically over the last decade, mainly due to increased awareness, availability of newer diagnostic modalities such as magnetic resonance imaging (MRI) and newer, more powerful treatments such as biologics. Imaging of the small bowel is needed for diagnosis, management, follow-up and also evaluation of the disease in terms of location, extent, activity and complications. We review all the methods (barium examinations, ultrasonography, computed tomography, MR, and computed tomography-positron emission tomography) commonly used for imaging the small bowel in paediatric patients with Crohn's disease analyzing the advantages and disadvantages of each modality, with particular emphasis on MR imaging.

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“…Several studies showed a relation among bowel wall thickness, clinical disease activity and endoscopic findings, using the Crohn's Disease Activity Index (CDAI) at initial diagnosis and during the clinical course of CD [23,24]. In particular, patients with a wall thickness of more than 7 mm have an increased risk of surgery [25].…”

Section: Ultrasonographic Features Of the Intestinal Wall In Crohn's mentioning

confidence: 99%

Ultrasonographic findings in Crohn’s disease

2014

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In recent years transabdominal bowel sonography has become a first-line modality both in the diagnosis and in the follow-up of inflammatory bowel diseases, especially Crohn's disease, reaching values of sensitivity ranging from 84 to 93 %. In particular, its role is very useful in the early diagnosis of complications such as stenosis, phlegmons, abscesses and fistulae. According to the available literature the ability of US to provide information about disease activity is still under debate and further studies are necessary. In this regard, of fundamental importance is the use of additional techniques such as color-and power-Doppler and contrast-enhanced ultrasound. The purpose of this paper is to report the main sonographic intestinal and extraintestinal findings detectable in Crohn's disease.Keywords Transabdominal bowel sonography Á Crohn's disease Á Color and power Doppler Á CEUS Á Disease activity Riassunto Nel corso degli ultimi anni l'ecografia delle anse intestinali è andata affermandosi come metodica di prima linea nella diagnosi e nel follow-up delle malattie infiammatorie croniche intestinali, soprattutto nella malattia di Crohn, con valori di accuratezza diagnostica dell'84-93 %. In particolare il suo ruolo risulta preminente nella precoce diagnosi delle complicanze, quali stenosi, flemmoni, ascessi e fistole. In accordo con la letteratura disponibile più discussa rimane la capacità di fornire informazioni circa l'attività di malattia ed ulteriori studi appaiono necessari. A tal proposito è fondamentale l'utilizzo di metodiche quali color e power Doppler e l'ecografia con mezzo di contrasto (CEUS). Scopo del presente lavoro è quello di riportare i principali quadri ecografici intestinali ed extra-intestinali evidenziabili nella malattia di Crohn.

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Bowel Wall Thickness at Abdominal Ultrasound and the One-Year-Risk of Surgery in Patients with Crohn's Disease

Cited by 65 publications

References 25 publications

The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

Imaging of the small bowel: Crohn’s disease in paediatric patients

Ultrasonographic findings in Crohn’s disease

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