Bovine Vibriosis Vaccination

Abstract

An adjuvant vaccine was prepared from an Australian isolate of Campy-lobacter fetus subsp fetus biotype intermedius and injected into 23 virgin Guernsey heifers. Ten nonvaccinated animals served as controls. When challenged by the intravaginal route with a culture of either the homologous strain or biotype venerealis, weekly swabs from the anterior vagina continued to yield either biotype in 8 of 10 nonvaccinates at 6 weeks as compared with 3 of 23 vaccinates. Serology in vaccinated heifers and rabbits showed that the vaccine produced high titres of antibody against both homologous and heterologous strains.

Immunization in heifers with dual vaccines containing Tritrichomonas foetus and Campylobacter fetus antigens using systemic and mucosal routes

“…The supplemental vaginal challenge with T. foetus and C. fetus venerealis in our experiment was utilized in another T. foetus-only immunization trial [13]; we used an inoculation concentration coincident with C. fetus [32] and T. foetus [18] artificial infections. This allowed us to ensure infectivity (high incidence of dual infection in all groups) and to put the vaccines to an excessive challenge, where the experimental demonstrated a better performance, that was less evident in natural breeding only.…”