Bovine milk fat components inhibit food-borne pathogens

Sprong, R. Corinne; Hulstein, Marco F. E.; Meer, Roelof van der

doi:10.1016/s0958-6946(01)00139-x

Cited by 80 publications

(62 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Additionally, some PL, such as sphingomyelin (SM) and phosphatidylcholine (PC), are mainly located in the outer leaflet of the plasma membrane of cells, including the epithelial cells of mammary tissue, and they appear at the surface of the milk fat globule membrane (Morin et al, 2007) and could be involved in binding processes and participate in the protection of new-borns against enteropathogens. In this sense, the binding of Helicobacter subspecies to phosphatidylethanolamine (PE) has been reported (Sprong et al, 2002) Milk from ewes and goats is currently used in the dairy industry for the manufacturing of cheese because of its fat and protein contents (Boyazoglu and Morand-Fehr, 2001;Raynal-Ljutovac et al, 2008), and it also affords a high amount of byproducts such as buttermilk, whey, and whey cream, which are increasingly appreciated by consumers (Michaelidou, 2008). The PL concentration of such products (buttermilk, etc) is low, and several technological procedures have been developed to increase this content and reduce non-polar lipids at the same time.…”

Section: Analytical Proceduresmentioning

confidence: 99%

See 1 more Smart Citation

Phospholipid classes and fatty acid composition of ewe’s and goat’s milk

et al. 2013

View full text Add to dashboard Cite

RESUMEN Contenido de ácidos grasos de las diferentes clases de fosfolípidos de la leche de oveja y de cabraSe ha analizado el contenido, distribución de las especies individuales y la composición en ácidos grasos de los fosfolípidos (FL) de la leche de oveja y de cabra. Se ha estudiado también la unión de cepas enterotoxigénicas y uropatogénicas de Escherichia coli a estos compuestos y el efecto de los FL sobre la hemaglutinación provocada por estas bacterias mediante inmunodetección en placa y ensayos en placas multipocillo, respectivamente. La leche de oveja y de cabra contiene más FL que la de vaca, pero menos que la leche humana. El perfil de FL individuales es similar en la leche de oveja y de cabra e incluye esfingomielina, fosfatidilcolina, fosfatidiletanolamina, fosfatidilserina y fosfatidilinositol. En cuanto a la composición en ácidos grasos, los FL de ambos tipos de leche presentan un contenido elevado de ácidos grasos de cadena larga (más de 16 carbonos) y no saturados, siendo el más abundante C18:1. La leche de oveja contiene ácidos grasos más largos y menos saturados, mientras que los de la leche de cabra son más cortos y más saturados. No se ha encontrado adhesión de ninguna de las cepas bacterianas estudiadas a los FL individuales de la leche de oveja o de cabra .Tampoco se ha observado inhibición de la hemaglutinación producida por las bacterias por los FL. Estos compuestos son constituyentes fundamentales de la membrana de los glóbulos de grasa de la leche, pero a la vista de los resultados obtenidos, no parece que participen en la defensa del recién nacido frente a infecciones bacterianas. PALABRAS CLAVE: Ácidos grasos -Adhesión bacteriana -Fosfolípidos -Leche de cabra -Leche de oveja. SUMMARY Phospholipid classes and fatty acid composition of ewe's and goat's milksThe content, distribution of individual species, and the fatty acid composition of phospholipids (PL) from ewe's and goat's milk were analyzed. The binding of enterotoxigenic and uropathogenic Escherichia coli strains to PL and the inhibition of bacterial hemagglutination by PL were addressed using high performance thin-layer chromatography-overlay assays and microtiter plates, respectively. Ovine and caprine milk contained more PL than bovine milk but less than human milk. The profile of individual PL was similar, including sphingomyelin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine and phosphatidylinositol in both ovine and caprine milk. Regarding the fatty acid composition, a high content of long-chain fatty acids (more than C16) and unsaturated fatty acids, with C18:1 as the most abundant was found in ovine and caprine milk PL. Ovine milk has longer and less saturated fatty acids while caprine milk has shorter and more saturated ones. Neither the adhesion of any bacterial strains assayed to the individual PL from ovine or caprine milk nor the inhibition of bacterial hemagglutination by PL were observed. These are important constituents of the milk fat globule membrane, but it seems that they do not play a ro...

show abstract

Section: Analytical Proceduresmentioning

confidence: 99%

“…These membranes contain PL and could participate in the defence of newborns against infections (Sprong et al, 2002). Accordingly, we assayed the binding of ETEC and UPEC to ovine and caprine milk PL that had been separated by HPTLC.…”

Section: Phospholipid Classes and Fatty Acid Composition Of Ewe's Andmentioning

confidence: 99%

Phospholipid classes and fatty acid composition of ewe’s and goat’s milk

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Some studies have demonstrated the anticarcinogenic potential of phospholipids, especially against colon cancer (Dillehay et al, 1994;Schmelz et al, 1996Schmelz et al, , 1998, as well as their protective effect against bacterial toxins and infection (Rueda et al, 1998;Sprong et al, 2002). The antimicrobial activity of RT 3 and RT 4 prepared by blending dahi with fermented paneer whey in 40 and 30 per cent, respectively had significant higher antimicrobial activity against selected pathogens compared to the control RT 5 (containing 70 per cent dahi with 30 per cent water).…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Biofunctional Properties of Cultured Buttermilk Prepared by Incorporation of Fermented Paneer Whey

Parekh¹,

Sadasivam²,

Hati³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

“…Sphingolipids and metabolites Reduction of the number of aberrant crypt foci and adenocarcinomas Dillehay et al [1994] Shift in tumor type (malignant → benign) Schmelz et al [1996; Symolon et al [2004]; Spitsberg [2005] Anticholesterolemic Noh & Koo [2003; Nyberg et al [2000]; Eckhardt et al [2002] Protection of the liver from fat-and cholesterolinduced steatosis Duivenvoorden et al 2006 Suppression of gastrointestinal pathogens Sprong et al [2002]; Vesper et al [1999]; Pfeuffer & Schrezenmeir [2001] Neonatal gut maturation Oshida et al [2003] Myelination of the developing central nervous system Oshida et al [2003] Endogenous modulators of vascular function Michel et al [2007] Associated with age-related diseases and the development of Alzheimer Parodi [2001]; Spitsberg [2005] Sphingosine 1-phosphate Mitogenic Zhang et al [1990Zhang et al [ , 1991 Phosphatidyl-serine (PS) Restore normal memory on a variety of tasks McDaniel et al [2003] Positive effects on alzheimer patients Crook et al [1992]; Heiss et al [1994]; Pepeu et al [1996]; Gindin et al [1998]; Hashioka et al [2004] Improve exercise capacity of exercising humans Kingsley [2006] Phosphatidylcholine (PC) Support liver recovery from toxic chemical attack or viral damage Kidd [2002] Protects the human GI mucosa against toxic attack Anand et al [1999] Reduction of necrotising enterocolitis Carlson et al [1998] Lysophosphat-idylcholine (lyso PC) Bacteriostatic and bactericidal capacity van Rensburg et al [1992] Strong gastroprotective role in the duodenal mucosa ; ; Kivinen et al [1995] Other components Vitamin E and carotenoids Antioxidants Spitsberg [2005] as a mediator of senescence in a cell culture...…”

Section: Polar Lipidsmentioning

confidence: 99%

“…When infants are given a formula supplemented with gangliosides, significantly fewer Escherichia coli and more bifidobacteria were observed in their faeces than those of the control group [Rueda et al, 1998]. Sprong et al [2001Sprong et al [ , 2002 even reported direct in vitro bactericidal activities of digestion products of sphingolipids. Ceramide was not bactericidal at the tested concentration of 100 mmol/L, but lysophingomyelin appeared highly bactericidal against Campylobacter jejuni, Listeria monocytogenes and Clostridium perfringens, and showed moderately lowered viable counts of E. coli and Salmonella enteritidis.…”

Section: Bactericidal Effect Of Sphingolipidsmentioning

confidence: 99%

Composition, Properties and Nutritional Aspects of Milk Fat Globule Membrane – A Review

El-Loly¹

2011

Pol. J. Food Nutr. Sci.

View full text Add to dashboard Cite

processes and defense mechanisms in the newborn [Cavaletto et al., 2006].The stabilizing membrane acts as reactive sorts on the interface between the barriers of milk serum. As such, it can be globule and rate-controlling for a host of physical and of enzymes chemical interactions, e.g., binding mace elements; controlled release of the polar materials products of lipolysis; transfer of milk serum; maintenance of emulsion into stability by prevention of globule fusion; availability of fatty acids and cholesterol for micellar absorption in the small intestine; and destabilization by creaming, clumping, churning, freeze-thaw, and heating, resulting in loosely bound substances into milk transfer serum. Worthy of notice is that the interactions are dynamic.Moreover, it is assumed that the MFGM proteins also possess specific nutritional properties. As such, due to their origin, composition and structure, MFGM polar lipids and proteins could be used as an emulsifier or stabilizer, combining technological and nutritional functionality [Mulder & Walstra, 1974;Anderson & Cawston, 1975;Patton & Keenan, 1975;Patton & Jensen, 1975, 1976Keenan et al., 1983;Mather & Keenan, 1983; McPherson & Kitchen, 1983; Walstra & Jenness, 1984;Keenan & Dylewski, 1985 Bucbheim, 1986;Mather, 1987; Keenan et al., 1988;Keenan & Dylewski, 1995;Keenan & Patton, 1995;Mather & Keenan, 1998;Danthine et al., 2000; Keenan, 2001; Keenan & Mather, 2002; Ollivier--Bousquet, 2002;Lopez et al., 2006Lopez et al., , 2007Sanchez-Juanes et al., 2009;Zamora et al., 2009]. Composition, Properties and Nutritional Aspects of Milk Fat Globule Membrane -a Review Mohamed Mansour El-Loly Dairy Department, National Research Centre, Dokki, Cairo, EgyptKey words: milk fat globule membrane, mammary gland, isolation, structure, stability, nutritional, nutraceuticalIn the last few years, knowledge on the composition and properties of the milk fat globule membrane (MFGM) increased significantly. It is now recognized that the MFGM is highly complex in structure and composed of different protein and lipid components with specific technological and nutritional properties. As such, MFGM materials have been isolated and characterized as valuable ingredients for incorporation into new food products. However, MFGM are also sensitive to modification during isolation and processing, and care should be taken to standardize the composition and characteristics of the membrane to maintain its unique properties during application in food products.The MFGM is subject to changes in composition and structure from the moment the fat globule leaves the mammary secretory cell. Upon milk harvesting and further milk handling, further changes to the MFGM take place. Depending on the type and degree of treatment, this may involve different physico-chemical interactions between various membrane components, the loss of membrane components and/or adsorption of components from the milk plasma. However, the effects appear to be variable and dependent on physiological (animal) factors, and much remains ...

show abstract

Bovine milk fat components inhibit food-borne pathogens

Cited by 80 publications

References 30 publications

Phospholipid classes and fatty acid composition of ewe’s and goat’s milk

Phospholipid classes and fatty acid composition of ewe’s and goat’s milk

Biofunctional Properties of Cultured Buttermilk Prepared by Incorporation of Fermented Paneer Whey

Composition, Properties and Nutritional Aspects of Milk Fat Globule Membrane – A Review

Contact Info

Product

Resources

About