Bovine Adenovirus

Abstract

Nine strains of an adenovirus serotype were recovered in bovine testicle cell cultures from Japanese cattle suffering with an acute febrile illness accompanied by rhinorrhea and diarrhea. The isolated virus was shown to have the physicochemical properties of the adenovirus group such as the nucleic acid type, the size and ultrastructure of the virion, and the resistance to ether and chloroform. The isolated virus produced eosinophilic intranuclear inclusion bodies characteristic of adenoviruses and the group specific antigen of adenovirus in bovine testicle cell culture. According to the results of crossneutralization tests the isolated virus represents a serological type distinct from bovine adenovirus types 1, 2 and 3 and from the Nagano virus. The isolated virus agglutinated erythrocytes of cattle, sheep, goat, 'guinea pig, rat, hamster and mouse, but not those of vervet monkey, horse, goose and chicken. HI test using cattle erythrocytes corroborated the results of serological typing by neutralization tests.

Complete Genome Sequence of Bovine Adenovirus Type 7 Strain Fukuroi, Isolated from a Cow with Respiratory Disease

“…B ovine adenovirus type 7 (BAdV-7), a member of the Atadenovirus genus of the Adenoviridae family, was first isolated in 1965 in our laboratory from blood samples from a Holstein cow with respiratory and enteric disease (1)(2)(3). BAdV-7 is recognized as one of the most important respiratory and enteric pathogens for the cattle industry (1,4). Currently, bovine vaccines available in Japan contain BAdV-7 (http://www.kyotobiken .co.jp/en/products/cow.html#respiration).…”

Ibaraki Virus, an Agent of Epizootic Disease of Cattle Resembling Bluetongue

“…The causative agent of bovine epizootic fever has been identified and is distinct from Ibaraki virus [12,13,19].…”

Adenoviruses of Vertebrate Animals

“…While the subgroup 1 viruses fully share a common antigen with human adenoviruses, the subgroup 2 viruses have only a weak relationship. However, Inaba et al (1968) showed that there was as much sharing of antigens between human strains and B4 and B7 as there was between B4 and B7. Support for these findings has come from other workers (Tanaka^/ al., 1968;Mohanty, 1971;Rondhuis, 1973;Mattson et al, 1977).…”