Adenoviruses of Vertebrate Animals

McFerran, J.B.

doi:10.1016/b978-0-12-429703-6.50009-1

Cited by 12 publications

(9 citation statements)

References 294 publications

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“…34 Md. Saifuddin and C. R. Wilks IBH virus, family Adenoviridae, genus Ariadenovirus, is shed in feces and usually spreads laterally through contaminated food, water and litter within sheds [11]. Evidence for vertical transmission has also been presented [15].…”

Section: Introductionmentioning

confidence: 97%

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Pathogenesis of an acute viral hepatitis: inclusion body hepatitis in the chicken

Saifuddin

Wilks

1991

Archives of Virology

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The pathogenesis of inclusion body hepatitis was studied following the oral administration of a serotype 8 strain of avian adenovirus into 2-day-old specific pathogen free chickens. Viral antigens were detected in tissues at various times post inoculation (pi) by enzyme-linked immunosorbent assay and by immunocytochemistry. Viral antigens were detected in intestinal epithelium from 12h to 13 days pi and in the plasma fraction of blood by 24 h pi. A biphasic, cell-free viremia with peaks at 2 and 7 days pi was recorded. Antigens were first detected in the liver from 2 days and reached peak levels at 6 days pi. The second peak of viral antigens in blood plasma was probably due to release of virus from damaged hepatic cells. Initially, viral antigens in the liver were restricted to cells lining the sinusoids but increasing involvement of hepatocytes occurred with time. Small amounts of viral antigens were detected in other tissues. Following the appearance of neutralizing antibodies in serum from 7 days pi, the levels of viral antigens in all tissues decreased and were undetectable by 15 days pi. This viral hepatitis of chickens is possibly a useful model for other viral infections where a cell-free viremic phase is important for spread of virus from primary sites to target organs, such as the liver.

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Section: Introductionmentioning

confidence: 97%

“…Inclusion body hepatitis (IBH) is an acute infectious disease of young chickens of 2-7 weeks of age caused by several serotypes of group I avian adenovirus (AAV) [11]. Natural outbreaks are characterized by a sudden onset of sharply increased flock mortality (10-30%), a short clinical course, anemia and necrotic hepatitis.…”

Section: Introductionmentioning

confidence: 99%

Pathogenesis of an acute viral hepatitis: inclusion body hepatitis in the chicken

Saifuddin

Wilks

1991

Archives of Virology

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“…The diagnosis of IBH due to adenovims infection is based on the macroscopic and microscopic lesions, especially the presence of basophilic intranuclear inclusion bodies associated with adenovirus-like particles in the hepatocytes situated in the periphery of necrotic foci. The viral particles observed using electron microscopy are consistent, both in size and morphology with adenovirus (McFerran, 1981); they did not resemble herpesvirus (Roizman, 1982). The epizootiological features of sudden presentation, acute progression and elevated mortality are typical of some adenoviral infections reported in various avian species (Sileo et al, 1983;Coussement et al, 1984;Goryo et al, 1988).…”

mentioning

confidence: 59%

Inclusion body hepatitis (IBH) in a group of eclectus parrots (Eclectus roratus)

et al. 1992

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“…All of the examined flocks in the present study were positive for antibodies suggesting widespread EDS' 76 infection in this region of Egypt. The presence of high HI antibody titres suggests that infection was acquired at an early age and this could not be due to maternal antibodies as the present study was limited to birds 5 to l0 weeks old and maternally derived antibodies are known to persist only up to 3 weeks of age McFerran (1981), McFerran and Stuart (1990). Vertical transmission is common in EDS' 76 virus infection but congenitally infected birds may not become serologically positive until 25-28 weeks of age VanEcz (1982).…”

Section: Aiv-(h9)mentioning

confidence: 82%

“…AAV were frequently isolated from the respiratory and/or intestinal tracts of the apparently healthy chickens, and their role in the etiology of clinical disease was regarded as insignificant Yates et al (1976) and Winterfield (1984). Sometimes., AAVs were associated with a variety of specific disease such as (quail bronchitis, inclusion body hepatitis (IBH), egg drop syndrome (EDS), turkey hemorrhagic enteritis (THE), marble spleen disease and respiratory manifestation) Du Bose et al (1958), Du Boes and Grumbles (1959), Ismail (1966), Ahmed and El-Sisi (1969), Fadly and WinterfieId (1973, Rosenberger et al (1974), Hoffmann et al (1975), McFerran (1981, McFerran (1989), McFerran (1991) and McFerran and Stuart (1990). Papanikoloau et al (1985) and McFerran and Stuart 1990).…”

Section: Aiv-(h9)mentioning

confidence: 99%

Epidemiological Highlights on Some Viruses Associated With Increased Mortality in Chickens Bred in Sharkia Governorate.

H.A.A.

O.A.

2015

Assiut Veterinary Medical Journal

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In the present study 1317 serum samples obtained from 6 broiler flocks, 2 broiler breeders and 28 commercial layer flocks were examined for HI antibodies of {NDV, IBV 4/91,, AIV (H5N1, H5N2, H5N3, H9, H7) and Adenov (EDS 76 )}. Studying the vaccination protocols in flocks under investigation and their seroconversion had led us to speculate and conclude viral affections in the different localities of Sharkia governorate. Speculating viral affections was a very hard task because the Egyptian market is jammed with a great variety of protective vaccines this was conflicting during result interpretation. Positive immune titers for AIV-H7 in sharkia governorate was detected at June /2014 in (El-salhia, 10 th of Ramadan, El-ibrahemia and Abo-hammed) in commercial layer flocks only. The seropositive samples that exceeded the cutoff values were 63 out of 1317 (4.8%). AIV-H9 high seropositive immune titers was constantly found in examined samples although their protective vaccines were neglected. AIV-H 5 N 3 seropositive results was recorded in a totally non vaccinated flocks against H 5 which reflect virus circulation in the poultry premises. Seropositive titer for IBV-D 274 and EDS 76 was recorded in a totally non vaccinated flocks against such antigens., which refer to their role in the total simultaneous incidence of disease and consequent mortality. From another point of view it should be noted that. Vaccinating chicken flocks following a ready made manuscript of the producing companies without prior evaluation of the maternally derived antibodies (MDA) or evaluating the immune titers before taking the decision of vaccination or even considering the disease situation in the area is possible cause for vaccine failure. Sentinel birds inclusion in poultry patches should be taken seriously to give a mirror for the circulating viral agents in the poultry premises. It worth to mention that a parallel bacteriological work was running during investigation of the causes of increased mortality or dropped egg production. This work revealed the isolation of a resistant bacteria of the (Kebseilla spp).

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Adenoviruses of Vertebrate Animals

Cited by 12 publications

References 294 publications

Pathogenesis of an acute viral hepatitis: inclusion body hepatitis in the chicken

Pathogenesis of an acute viral hepatitis: inclusion body hepatitis in the chicken

Inclusion body hepatitis (IBH) in a group of eclectus parrots (Eclectus roratus)

Epidemiological Highlights on Some Viruses Associated With Increased Mortality in Chickens Bred in Sharkia Governorate.

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