Boundary lubrication and friction of polyethylene and polyamides under protein-containing solutions

Widmer, M.R.; Heuberger, Manfred; Spencer, Nicholas D.

doi:10.1016/s0167-8922(02)80040-2

Cited by 4 publications

(1 citation statement)

References 16 publications

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“…Ishihara et al (15) and Tanaka et al (16), (17) suggested that free water fraction on the polymer surface makes protein reversible adsorption. Spencer et al (18), (19) indicated the efficacy of albumin boundary film for friction. They pointed out the importance of surface hydrophilicity and albumin of native conformation on the lubricating ability.…”

Section: Discussionmentioning

confidence: 99%

Study on Wear Reduction Mechanisms of Artificial Cartilage by Synergistic Protein Boundary Film Formation

Nakashima

Sawae

Murakami

2005

JSME Int. J., Ser. C

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Poly(vinyl alcohol) (PVA) hydrogel is one of the anticipated materials for artificial cartilage. PVA hydrogel has high water content and a low elastic modulus similar to natural cartilage, but its major disadvantage is its lower strength. PVA hydrogel experienced rapid wear under severe conditions such as mixed or boundary lubrication. Therefore, the existence of a protective surface film with low friction becomes important to prevent surface failure. In this study, the reciprocating frictional tests for a sliding pair of PVA hydrogel and glass plate were carried out, and fluorescent observations were performed to identify the roles of adsorbed protein film. Albumin and γ-globulin, which are contained in natural synovial fluid, were used by mixing into the lubricant. It appears that groups of albumin molecules adsorb on the smooth γ-globulin adsorbed layer at content of 2.1 wt% of proteins with an appropriate ratio. But in the case of a lubricant which has excessive protein at 2.8 wt%, albumin and γ-globulin adsorbed separately. Considering the wear reduction at 2.1 wt% content of protein, albumin and γ-globulin constituted synergistic adsorbed film for wear reduction. It is indicated that albumin constructs a low shear layer and γ-globulin forms a layer protecting PVA hydrogel from wear. It is considered that wear and friction of PVA hydrogel were reduced due to slip of the boundary of adsorbed albumin and γ-globulin layer. Content of protein and ratio of albumin to γ-globulin (AG ratio) are important to constitute the appropriate protein film.

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Section: Discussionmentioning

confidence: 99%

Study on Wear Reduction Mechanisms of Artificial Cartilage by Synergistic Protein Boundary Film Formation

Nakashima

Sawae

Murakami

2005

JSME Int. J., Ser. C

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Influence of protein conformation on frictional properties of poly (vinyl alcohol) hydrogel for artificial cartilage

2007

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Poly (vinyl alcohol) (PVA) hydrogel is one of the anticipated materials for artificial cartilage. In our previous studies, wear of PVA hydrogel depended on content of proteins in lubricants. The secondary structures of bovine serum albumin (BSA) and human gamma globulin (HGG) were investigated in circular dichroism spectroscopy to clarify the influence of the proteins on frictional properties. BSA and HGG were mainly composed of the a-helix and the b-sheet, respectively. BSA containing the a-helix structure showed low friction compared to HGG composed of the b-sheet structure in mixed or boundary lubrication mode. The a-helix structure forms low shear layer because the a-helix structure is easily released from surfaces and low cohesive strength. HGG forms uniform adsorption layer, but showed higher friction than BSA in the rubbing with single protein. In the repeated rubbing with changing of lubricants from HGG to BSA, however, the final friction was reduced, because an optimum layered structure of proteins was formed. Hence, layered structure of proteins appears to play an important role to protect rubbing surfaces and to reduce friction. In heat treatment tests, heat-induced BSA showed very low friction because of reduction of the a-helix structure. Heat-induced HGG did not show large differences from native HGG, but could not bring low friction with heat-induced BSA. Thus it was shown that the protein conformation has effective influences on friction.

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Protein-mediated boundary lubrication in arthroplasty

et al. 2005

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Boundary lubrication and friction of polyethylene and polyamides under protein-containing solutions

Cited by 4 publications

References 16 publications

Study on Wear Reduction Mechanisms of Artificial Cartilage by Synergistic Protein Boundary Film Formation

Study on Wear Reduction Mechanisms of Artificial Cartilage by Synergistic Protein Boundary Film Formation

Influence of protein conformation on frictional properties of poly (vinyl alcohol) hydrogel for artificial cartilage

Protein-mediated boundary lubrication in arthroplasty

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