Botryoid Rhabdomyosarcoma of the Urinary Bladder in a Filly

Abstract

Neoplasia of the equine urinary bladder is seldom reported in the literature and is considered uncommon.2,7 Clinical cases are rarely described, and those reported often involve slaughterhouse studies. Of those tumors of the urinary bladder reported, most occurred in aged mares, although aged geldings were also affected. 2,7,9 Benign tumors of the urinary bladder include papillomas, adenomas, fibromas, leiomyomas, angiomas, and fibroepithelial polyps. 9,10 There are several reports of malignant tumors; however, the vast majority of cases were documented in the early 1900s.3 Squamous cell carcinoma and transitional cell carcinoma have been most frequently identified in the literature. 2,4,7 This report describes a malignant primary urinary bladder tumor in a filly.A 2-year-old Appaloosa filly was presented to the University of Missouri Veterinary Teaching Hospital with a brief history of stranguria and hematuria. A large multinodular mass protruded into the vagina through a markedly dilated urethral orifice. The mass was debulked, and representative samples were submitted to the Veterinary Medical Diagnostic Laboratory at the University of Missouri. A tentative diagnosis of botryoid rhabdomyosarcoma was made at this time, and the owners elected to take the filly home despite the poor prognosis. Approximately 3 months later, stranguria recurred and the filly was returned to the teaching hospital. Rectal palpation revealed a mass caudal to the left kidney, and the decision was made to euthanize the filly because of From the Veterinary Medical Diagnostic Laboratory (Tumquist, Pace, Kreeger, Bailey), the Veterinary Teaching Hospital (Keegan,

Congenital tumours and tumour‐like lesions in domestic animals. 3. Horses. A review

“…Loss of appetite and weight and pleural effusion were found in a 3 years old gelding (49 Two cases of embryonal botryoid rhabdomyosarcoma were reported to occur in young horses (63,65). A yearling filly was treated by ovariectomy for a large uterine tumour (18 kg!).…”

“…A large mass protruding into the vagina was debulked in a 2 years old filly (65). At necropsy three months later a large tumour (10x6x3 cm.)…”

Transitional cell carcinoma of the urinary bladder in a 12‐year‐oldBelgianWarmblood gelding

“…Failed attempts to surgically excise a rhabdomyosarcoma and a SCC have also been previously described (Turnquist et al . ; Gandini et al . ).…”

“…Whilst transitional cell carcinoma (TCC) is the most frequently reported primary bladder neoplasm in the dog (Mutsaers et al 2003) and man (Johansson and Cohen 1997), it has rarely been reported in the horse with only 5 previously published cases (Traub et al 1983;Fischer et al 1985;Servantie et al 1986;Turner et al 1995;Patterson-Kane et al 2000). Other reports of neoplasia of the horse bladder include lymphosarcoma, leiomyosarcoma, fibromatous polyp and rhabdomyosarcoma (Sweeney et al 1991;Turnquist et al 1993;Hurcombe et al 2008; Barrell and Hendrickson 2009;Waldridge 2010).…”

Vaginal Rhabdomyosarcoma in a Dog

“…It has been reported to occur most commonly in the urinary bladder of large-breed dogs aged less than 2 years and has also been reported to occur in the urinary bladder of a smallbreed dog (Maltese) and a horse. 7,9 There is only one report of its occurrence in an organ other than the urinary bladder, i.e., in the uterus of a horse. 8 In this article, we describe the histopathology of botryoid rhabdomyosarcoma of the vagina in dogs.…”