Both Short and Long Sleep Durations are Risk Factors for Sarcopenia in Suburban-Dwelling Older Chinese Individuals: A 3-Year Longitudinal Study

Han, Peipei; Hou, Lin; Liang, Zhenwen; Chen, Wuxiong; Li, Junxue; Cheng, Yazhou; Zhou, Wei; Zeng, Siya; Pan, Jiangtao; Xu, Lanshan; Wang, Yi; Chen, Yangyi; Guo, Qi

doi:10.2147/nss.s361925

Cited by 11 publications

(5 citation statements)

References 31 publications

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“…We noted that the majority of PSA group members had shorter sleep duration and lower bodyweight. The present results are in line with that of a prospective study 29 . Sleep is the time when several growth‐related hormones are produced, including those that promote muscle repair, tissue growth and protein synthesis.…”

Section: Discussionsupporting

confidence: 91%

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Association of possible sarcopenia with major chronic diseases and multimorbidity among middle‐aged and older adults: Findings from a national cross‐sectional study in China

Zhao,

Zhang,

et al. 2023

Geriatrics Gerontology Int

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AimThis study investigated the prevalence of possible sarcopenia (PSA) in a large sample of middle‐aged and older adults, and determined the association between PSA, major chronic diseases and the number of chronic diseases.MethodsA total of 14 917 adults aged ≥40 years were included in the analysis. The handgrip strength and the five‐time chair stand test were used to assess PSA. The participants' major chronic diseases were divided into 14 categories. Four categories were created based on the participants' number of chronic illnesses: 0, 1, 2 and ≥3.ResultsThe present study found an overall prevalence of PSA of 23.6% among Chinese middle‐aged and older adults aged ≥40 years, with the risk increasing with advancing age. PSA was significantly associated with most categories of chronic diseases and multimorbidity. The closely independent associations were obtained for stroke; emotional, nervous or psychiatric problems; chronic lung disease, asthma, heart disease, hypertension and arthritis or rheumatism. Compared with participants with 0 chronic disease, those with two or more chronic diseases had higher odds for PSA. However, the association between PSA and the number of chronic diseases varied in different sex and age groups.ConclusionsThe findings suggest that PSA is associated with major chronic diseases among middle‐aged and older adults. People with two or more chronic diseases have a greater likelihood of PSA compared with those without chronic diseases, and the association between PSA and the number of chronic diseases largely depended on sex and age. Geriatr Gerontol Int 2023; ••: ••–••.

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Section: Discussionsupporting

confidence: 91%

“…The present results are in line with that of a prospective study. 29 Sleep is the time when several growthrelated hormones are produced, including those that promote muscle repair, tissue growth and protein synthesis. Decreased sleep duration has an impact on skeletal muscle protein synthesis and degradation.…”

Section: Discussionmentioning

confidence: 99%

Association of possible sarcopenia with major chronic diseases and multimorbidity among middle‐aged and older adults: Findings from a national cross‐sectional study in China

Zhao,

Zhang,

et al. 2023

Geriatrics Gerontology Int

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“…This suggested that habitual long sleep duration in older adults is detrimental to muscle mass loss. This result was consistent with other longitudinal studies [ 19 , 20 ].A longitudinal study [ 21 ] of Chinese older adults found that both longer and shorter sleep duration were associated with muscle loss. The difference was that the study was conducted with older adults in rural and suburban China, whereas our study focused on community-based older adults in a large city.…”

Section: Discussionmentioning

confidence: 99%

“…Sleep is recognized as an important factor in maintaining muscle mass [16].Several cross-sectional studies [17,18] had demonstrated an association between too much or too little sleep and decreased muscle mass in older adults. The validity of research hypotheses requires evidence to further demonstrate causality, but there are fewer longitudinal studies [19][20][21]in this area. The results of related studies suggested that sleep duration affects muscle mass decline in older adults, and gender differences in the effect of sleep duration on muscle mass decline have not been consistent across these studies.…”

Section: Introductionmentioning

confidence: 99%

Sleeping more than 8 h: a silent factor contributing to decreased muscle mass in Chinese community-dwelling older adults

Huang,

Lin,

Xiao

et al. 2024

BMC Public Health

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Background Muscle mass loss is an age-related process that can be exacerbated by lifestyle, environmental and other factors, but can be mitigated by good sleep. The objective of this study was to investigate the correlation between varying time lags of sleep duration and the decline in muscle mass among individuals aged 60 years or older by using real-world health monitoring data obtained from wearable devices and smart home health monitoring devices. Methods This study included 86,037 observations from 2,869 participants in the Mobile Support System database. Missing data were supplemented by multiple imputation. The investigation utilized generalized estimating equations and restricted cubic spline curve to examine the relationship between sleep duration and low muscle mass. Various lag structures, including 0, 1, 2, 0–1, 0–2, and 1–2 months, were fitted, and the interaction effect of observation time with sleep duration was estimated for each lag structure. Additionally, subgroup analyses were conducted. The models were adjusted for various covariates, including gender, age, body mass index, footsteps, smoking status, drinking status, marital status, number of chronic diseases, number of medications, diabetes mellitus, hyperlipidemia, coronary artery disease, respiratory disease, and musculoskeletal disease and an interaction term between time and sleep duration. Results The results of the generalized estimating equation showed a significant correlation (p < 0.001) between sleep duration of 8 h or more and low muscle mass in older adults, using 6–7 h of sleep as a reference. This effect was seen over time and prolonged sleep accumulated over multiple months had a greater effect on muscle mass loss than a single month. The effect of long sleep duration on muscle mass loss was significantly greater in females than in males and greater in the over-75 than in the under-75 age group. Restricted cubic spline plots showed a non-linear relationship between sleep duration and low muscle mass (p < 0.001). Conclusions This study found an association between sustained nighttime sleep of more than eight hours and decreased muscle mass in older adults, especially older women.

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“…Future studies should aim to include a comprehensive set of measures to fully capture the multifaceted nature of sarcopenia and its clinical implications. Finally, multiple studies have reported a higher prevalence of sleep disorders and sarcopenia in older adults ( 45 , 46 ). However, dual-energy X-ray absorptiometry in NHANES is not suitable for individuals aged 60 years and older.…”

Section: Limitationsmentioning

confidence: 99%

Association between sarcopenia and sleep disorders: a cross-sectional population based study

Liu,

Luo,

Chen

et al. 2024

Front. Nutr.

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ObjectiveSleep disorders is a worldwide public health problem. We sought to examine the association between sarcopenia, a decline in skeletal muscle mass and function, and sleep disorders within the adult demographic of the United States during the period spanning 2011 to 2018.MethodsDiagnosis of sarcopenia and sleep disorders was ascertained through appropriate calculations and a structured questionnaire. The primary correlation analysis was conducted using a weighted multivariate logistic regression model. Furthermore, to confirm the presence of a potential non-linear association between sarcopenia and sleep disorders, additional analyses were performed using multivariate logistic regression and restricted cubic spline (RCS) regression with dose-response curve analysis. Subgroup analyses were also conducted to explore the influence of relevant socio-demographic factors and other covariates.ResultsThe final analysis encompassed 5,616 participants. Model 4, inclusive of all pertinent covariates, revealed a positive correlation between sarcopenia and sleep disorders, yielding an odds ratio (OR) of 1.732 (95% CI: 1.182–2.547; P = 0.002). Further analysis, utilizing the restricted cubic spline model, indicated a decreasing trend in sleep disorders as sarcopenia indices rose. Stratified analyses across diverse variables underscored the significant impact of sarcopenia on sleep disorders prevalence in several subgroups. Specifically, males, individuals aged 40 and above, non-Hispanic whites, those with high school education or equivalent, unmarried individuals, obese individuals (BMI ≥ 30), alcohol drinkers, former smokers, diabetics, and those engaging in less rigorous recreational activities exhibited a more pronounced association between sarcopenia and sleep disorders. The incidence of sleep disorders exhibited an upward trend as the incidence of sarcopenia declined among study participants.ConclusionsIn summary, our study provides evidence of an association between sarcopenia and the prevalence of sleep disorders, with a negative correlation observed between the sarcopenia index and the odds ratio of sleep disorders. These findings suggest that maintaining optimal muscle mass may have a beneficial impact on sleep-related issues. In terms of exploring the mechanisms underlying the relationship between sarcopenia and sleep disorders, more in-depth research is warranted to ascertain the definitive causal relationship.

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Both Short and Long Sleep Durations are Risk Factors for Sarcopenia in Suburban-Dwelling Older Chinese Individuals: A 3-Year Longitudinal Study

Cited by 11 publications

References 31 publications

Association of possible sarcopenia with major chronic diseases and multimorbidity among middle‐aged and older adults: Findings from a national cross‐sectional study in China

Association of possible sarcopenia with major chronic diseases and multimorbidity among middle‐aged and older adults: Findings from a national cross‐sectional study in China

Sleeping more than 8 h: a silent factor contributing to decreased muscle mass in Chinese community-dwelling older adults

Association between sarcopenia and sleep disorders: a cross-sectional population based study

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