Botanical Drugs in Traditional Chinese Medicine With Wound Healing Properties

Abstract

Chronic and unhealed wound is a serious public problem, which brings severe economic burdens and psychological pressure to patients. Various botanical drugs in traditional Chinese medicine have been used for the treatment of wounds since ancient time. Nowadays, multiple wound healing therapeutics derived from botanical drugs are commercially available worldwide. An increasing number of investigations have been conducted to elucidate the wound healing activities and the potential mechanisms of botanical drugs in recent years. The aim of this review is to summarize the botanical drugs in traditional Chinese medicine with wound healing properties and the underlying mechanisms of them, which can contribute to the research of wound healing and drug development. Taken together, five botanical drugs that have been developed into commercially available products, and 24 botanical drugs with excellent wound healing activities and several multiherbal preparations are reviewed in this article.

Moringa oleiferaLam.: a comprehensive review on active components, health benefits and application

“…Besides the use of chemical drugs, high prices, side effects and other problems, herbal remedies have attracted attention. 110 M. oleifera is widely used in wound treatment due to its low side effects and excellent antioxidant and antibacterial activity. In addition to the above functions, M. oleifera can also be used for bone protection, 91 promote coagulation 111 and so on.…”

Kampo herbal ointments for skin wound healing

“…This crude drug, not listed in the Japanese Pharmacopoeia, has similar attributes to purple gromwell root with the same characteristic purplish color even if they are related to different botanical genera ( The society of Japanese pharmacopeia, 2016 ). A. euchroma root is not only visually similar to purple gromwell root but also has many common compounds and therapeutic indications such as wound healing, antimicrobial, and antibacterial properties in Ayurvedic medicine and TCM ( Kumar et al, 2021 ; Ning et al, 2022 ).…”