Boosting cancer therapy efficiency <i>via</i> photoinduced radical production

Li, Yong; Wu, Meng-Si; Lan, Minbo

doi:10.1039/d1sc01220g

Cited by 8 publications

(1 citation statement)

References 45 publications

(49 reference statements)

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“…Narrow optical band gap can be relatively readily achieved through reasonable chemical modification and structural control [7] . Considering the good biocompatibility of the radical materials, they have attracted widespread attention in the development of photothermal conversion and biologic applications [3e, 8] . Compared with the other widely reported photothermal conversion materials such as inorganic materials, organic two‐dimensional framework, and conjugated polymer materials, [3c,d, 9] organic small molecules are relatively overlooked by researchers in this field.…”

Section: Introductionmentioning

confidence: 99%

Accessing Highly Efficient Photothermal Conversion with Stable Open‐Shell Aromatic Nitric Acid Radicals

et al. 2022

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It is very challenging to prepare stable radicals as they are usually thermodynamically or kinetically unstable in air. Herein, a series of star‐shaped aromatic nitric acid radicals were prepared via facile demethylation and consequent oxidation. As phenol radicals without steric hindrance group protection, they exhibit high electrochemical and thermal stability due to their rich resonance structures including closed‐shell nitro‐like and open‐shell nitroxide structure with unpaired electrons delocalized in conjugated backbones. Among them, TPA‐TPA‐O6 powder exhibited extremely wide absorption from 300 to 2000 nm covering the whole solar spectral irradiance, high photothermal conversion efficiency, and negligible photobleaching effect in seawater desalination. Under the irradiation of one sunlight, the water evaporation efficiency of TPA‐TPA‐O6 is recorded to be as high as 89.41 % and the water evaporation rate is 1.293 kg m−2 h−1, which represents the top performance in pure organic small molecule photothermal materials.

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Section: Introductionmentioning

confidence: 99%

Accessing Highly Efficient Photothermal Conversion with Stable Open‐Shell Aromatic Nitric Acid Radicals

et al. 2022

View full text Add to dashboard Cite

show abstract

Accessing Highly Efficient Photothermal Conversion with Stable Open‐Shell Aromatic Nitric Acid Radicals

et al. 2022

View full text Add to dashboard Cite

It is very challenging to prepare stable radicals as they are usually thermodynamically or kinetically unstable in air. Herein, a series of star-shaped aromatic nitric acid radicals were prepared via facile demethylation and consequent oxidation. As phenol radicals without steric hindrance group protection, they exhibit high electrochemical and thermal stability due to their rich resonance structures including closed-shell nitro-like and open-shell nitroxide structure with unpaired electrons delocalized in conjugated backbones. Among them, TPA-TPA-O 6 powder exhibited extremely wide absorption from 300 to 2000 nm covering the whole solar spectral irradiance, high photothermal conversion efficiency, and negligible photobleaching effect in seawater desalination. Under the irradiation of one sunlight, the water evaporation efficiency of TPA-TPA-O 6 is recorded to be as high as 89.41 % and the water evaporation rate is 1.293 kg m À 2 h À 1 , which represents the top performance in pure organic small molecule photothermal materials.

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Regulating the bacterial oxygen microenvironment via a perfluorocarbon-conjugated bacteriochlorin for enhanced photodynamic antibacterial efficacy

Chen

et al. 2022

Acta Biomaterialia

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Boosting cancer therapy efficiency via photoinduced radical production

Abstract: Current cancer therapy has been restricted by the hypoxia microenvironment of tumors, especially for strongly oxygen-dependent photodynamic therapy. To defeat hypoxia tumor, an oxygen-irrelevant radical nanogenerator PI/FBC is developed by...

Cited by 8 publications

References 45 publications

Accessing Highly Efficient Photothermal Conversion with Stable Open‐Shell Aromatic Nitric Acid Radicals

Accessing Highly Efficient Photothermal Conversion with Stable Open‐Shell Aromatic Nitric Acid Radicals

Accessing Highly Efficient Photothermal Conversion with Stable Open‐Shell Aromatic Nitric Acid Radicals

Regulating the bacterial oxygen microenvironment via a perfluorocarbon-conjugated bacteriochlorin for enhanced photodynamic antibacterial efficacy

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