Bone response to different strength orthodontic forces in animals with periodontitis

Garat, J; Gordillo, María E; Ubios, A. M.

doi:10.1111/j.1600-0765.2005.00809.x

Cited by 25 publications

(11 citation statements)

References 14 publications

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“…It is suggested that PDL cells under mechanical stimulation created by gum chewing may induce osteoclastogenesis through up-regulation of RANKL expression via PGe2 synthesis during orthodontic tooth movement, and resulted in faster tooth movement. It is in accordance with Garat et al, 8 that light continuous bite force accelerates bone remodeling and prevents from excessive bone resorption. Therefore, it is logical that gum chewing is able both accelerates orthodontic tooth movement, and prevents from excessive bone resorption.…”

Section: Root Resorptionsupporting

confidence: 75%

“…7 In addition, the application of continuous force to the tooth also triggers addition bone volume, which enhances remodeling. 8 Other theory is the hypofunctional periodontium concept which stated that in the absence or reduced occlusal function, the periodontium narrows, and its cushioning effect decreases which lead to increase vulnerability to root resorption during orthodontic movement.…”

mentioning

confidence: 99%

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A new concept in orthodontics: faster and healthier tooth movement by regularly consuming xyilitol chewing gum

Utomo

2007

Dent. J. (Majalah Kedokteran Gigi)

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Section: Root Resorptionsupporting

confidence: 75%

mentioning

confidence: 99%

A new concept in orthodontics: faster and healthier tooth movement by regularly consuming xyilitol chewing gum

Utomo

2007

Dent. J. (Majalah Kedokteran Gigi)

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“…An aim of orthodontic treatment of periodontal patients is to lessen the difficulty of toothbrushing and thus to prevent secondary occlusal trauma. Recently, several clinical and experimental studies have demonstrated that orthodontic treatment contributes to increased alveolar bone formation during the treatment of periodontitis (36, 37). As for animal models, a previous study on dogs reported a deleterious effect of orthodontic force on periodontal tissues during the active phase of plaque‐induced periodontitis (3), which is inconsistent with our mouse model result.…”

Section: Discussionmentioning

confidence: 99%

Reduction of orthodontic tooth movement by experimentally induced periodontal inflammation in mice

Okamoto¹,

Ohnishi

Bandow

et al. 2009

European J Oral Sciences

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Orthodontic therapy is known to have an aggravating effect on the progression of destructive periodontitis if oral hygiene is not maintained. However, it is largely unknown how active periodontitis affects the velocity of orthodontic tooth movement. In this study, we examined the effect of periodontal inflammation on orthodontic tooth movement using a mouse model. Orthodontic force was applied on the maxillary first molar of mice, with or without ligature wire to induce experimental periodontitis. The distance moved by the first molar was significantly reduced by the ligature-induced experimental periodontitis. Tartrate-resistant acid phosphatase staining revealed that the number of osteoclasts present during orthodontic treatment was lower in the pressure zone of alveolar bone in the presence of periodontal inflammation. Consistently, the expression level of receptor activator of nuclear factor-kappaB ligand (RANKL) in the pressure zone was decreased in the ligature group. By contrast, experimental periodontitis increased the expression of cyclooxygenase-2 mRNA in the periodontal tissues, while in vitro treatment with prostaglandin E(2) decreased extracellular signal-regulated kinase phosphorylation and RANKL expression induced by mechanical stress in osteoblasts. Taken together, these results suggest that the orthodontic force-induced osteoclastogenesis in alveolar bone was inhibited by the accompanying periodontal inflammation, at least partly through prostaglandin E(2), resulting in reduced orthodontic tooth movement.

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“…However, physiology changes such as to the alveolar bone density and soft tissue are difficult to identify. Most of the previous studies related to the tissue reaction of orthodontic treatment focused on the periodontal ligament (PDL) using histology approaches in animal models [1,2]. Few studies have investigated the biomechanical response of alveolar bone during orthodontic tooth movement [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Effects of orthodontic tooth movement on alveolar bone density

Chang

Huang

et al. 2011

Clin Oral Invest

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The object of this study was to evaluate the relationship between changes in the alveolar bone density around the teeth and the direction of tooth movement by using cone-beam computed tomography (CBCT). CBCT was used to measure the bone densities around six maxilla anterior teeth before and after 7 months of orthodontic treatment in eight patients. Each root was divided into three levels (cervical, intermediate, and apical) to determine whether the bone density change varied with the tooth level. Moreover, each level was divided into four regions (palatal, distal, mesial, and buccal sides). Three-dimensional computer models of the maxilla before and after orthodontic treatment were created to detect the direction of tooth movement. The percentage for all 144 samples [8 (patients) × 6 (teeth) × 3 (levels)] in which the side (palatal, distal, mesial, or buccal sides) of maximum bone density reduction (before and after orthodontic treatment) coincided with the direction of tooth movement was calculated; this was referred to as the "coincidence percentage". The bone density around the teeth reduced by 24.3 ± 9.5%. The average coincidence percentage for the eight patients was 59.0%. The coincidence percentages for the eight patients were 62.5%, 62.5%, and 52.1% at the cervical, intermediate, and apical levels, respectively. The obtained results demonstrate that the direction of tooth movement is associated with the side of maximum bone density reduction, and that CBCT is a useful approach for evaluating bone density changes around teeth induced by orthodontic treatment.

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Bone response to different strength orthodontic forces in animals with periodontitis

Abstract: Our study shows that application of orthodontic forces once periodontal infection has been controlled contributes to increasing alveolar bone volume, consequently improving bone quality.

Cited by 25 publications

References 14 publications

A new concept in orthodontics: faster and healthier tooth movement by regularly consuming xyilitol chewing gum

A new concept in orthodontics: faster and healthier tooth movement by regularly consuming xyilitol chewing gum

Reduction of orthodontic tooth movement by experimentally induced periodontal inflammation in mice

Effects of orthodontic tooth movement on alveolar bone density

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