Bone Regeneration Potential of Biphasic Nanocalcium Phosphate with High Hydroxyapatite/Tricalcium Phosphate Ratios in Rabbit Calvarial Defects

Pripatnanont, Prisana; Praserttham, Pongsakorn; Suttapreyasri, Srisurang; Leepong, Narit; Monmaturapoj, Naruporn

doi:10.11607/jomi.4531

Cited by 24 publications

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“…38,39 A common way to obtain a porous structure in calcium phosphate is by the sacricial template method. During this method, slurry is absorbed into a porous template (such as polyurethane sponge [91][92][93] or micron/nano-sized graphite 94 ) with desired porosity, then it is dried into a solid template for a certain time, followed by sintering the template until it is burnt away, leaving the desired porous structure.…”

Section: Intrinsic Factorsmentioning

confidence: 99%

Biological properties of calcium phosphate biomaterials for bone repair: a review

Chen

2018

RSC Adv.

138

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Section: Intrinsic Factorsmentioning

confidence: 99%

Biological properties of calcium phosphate biomaterials for bone repair: a review

Chen

2018

RSC Adv.

138

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“…xenograft are still involved in the clinical use, but they are associated with many problems like possibility of cross infection and chance of immune rejection of recipient (5) . Recently, various types of synthetic bone substitutes have been introduced for clinical applications (6) .…”

Section: Introductionmentioning

confidence: 99%

Bone Regenerative Potentiality of Nanostructured Biphasic Hydroxyapatite /Tricalcium Phosphate Prepared from Eggshell as a Bone Graft in Vivo

Zaker¹,

Deleme²,

Taqa³

2020

RDENTJ

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Aims: to evaluate the biological response to nano sized biphasic hydroxyapatite and tricalcium phosphate synthesized from eggshell. Materials and methods: Egg shell burned in furnace at 1000 C° for 1 hour. The part of resultant powder was treated chemically with phosphoric acid to form HA, other part of heated egg shell treated with nitric oxide and di-ammonium hydrogen phosphate to form TCP then the two products mixed mechanically at ratio 80%/20% (HA/TCP). The mixture turned to nanoparticles via mechanical attrition and sieving membrane and sent for TEM, the resultant material characterization checked by FTIR spectroscopy. Two defects of 2 mm prepared in the femoral bone of 20 rabbits one filled with prepared material (group A) and the other left empty as negative control (group B). Results: greater bone formation was founded in group A where statistically significant. Conclusions: biphasic hydroxyapatite and tricalcium phosphate nano particles synthesized from eggshell is effective in bone regeneration and could be used as bone substitute derived from source of no economic value.

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“…Hydroxyapatite and tricalcium phosphate are the most calcium ceramic applied as bone graft (8,9) . BCP composed of hydroxyapatite and tricalcium phosphate of different ratios.…”

Section: Introductionmentioning

confidence: 99%

Densitometric and Histomorphometric Analysis for Testing New Bone Substitutes (BLUE BONE®), a Comparative Study on Rabbits' Femoral Defect

Zaker¹,

Deleme²,

Taqa³

2020

RDENTJ

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Aims: to evaluate the osteogenic regeneration ability of new nanometric biphasic hydroxyapatite and tricalcium phosphate (80/20) BLUE BONE. Materials and methods: twenty domestic rabbits were used in the present study with two defects were created in the rabbit's femur, one filled with BLUE BONE material and the other defect were left empty as negative control. Densitometric and histomorphometric analysis measured at 3 days, 7 days, 14 days, and 28 days. Results: showed positive osteogenic properties of the BLUE BONE due to the osteoconduction properties. Conclusions: this study supports that BCP may have better application prospects for bone repair.

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Bone Regeneration Potential of Biphasic Nanocalcium Phosphate with High Hydroxyapatite/Tricalcium Phosphate Ratios in Rabbit Calvarial Defects

Cited by 24 publications

References 0 publications

Biological properties of calcium phosphate biomaterials for bone repair: a review

Biological properties of calcium phosphate biomaterials for bone repair: a review

Bone Regenerative Potentiality of Nanostructured Biphasic Hydroxyapatite /Tricalcium Phosphate Prepared from Eggshell as a Bone Graft in Vivo

Densitometric and Histomorphometric Analysis for Testing New Bone Substitutes (BLUE BONE®), a Comparative Study on Rabbits' Femoral Defect

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