Bone regeneration of multichannel biphasic calcium phosphate granules supplemented with hyaluronic acid

Taz, Mirana; Makkar, Preeti; Imran, Khan Mohammad; Jang, Dong-Woo; Kim, Yong-Sik; Lee, Byong‐Taek

doi:10.1016/j.msec.2019.02.051

Cited by 28 publications

(12 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Four F I G U R E 3 Transcrestal sinus lift procedure duplicate articles were excluded. Upon review of the full texts of these publications, studies performed in vivo that did not involve the use of HA in the oral cavity were excluded, including experimental studies that targeted the calvaria (Agrali et al, 2018;Diker, Gulsever, Koroglu, Yilmaz Akcay, & Oguz, 2018;de Brito Bezerra et al, 2012;Kim et al, 2007;Martínez-Sanz et al, 2011;Patterson et al, 2010;Pröhl et al, 2021;Silva et al, 2017;Townsend et al, 2020), the femur (Ahmed, Awartani, Niazy, Jansen, & Alghamdi, 2020;Nguyen & Lee, 2014;Taz et al, 2019), and the tibia (Aslan, Simsek, & Dayi, 2006). Two publications that focused on the use of HA for periodontal regeneration were also excluded.…”

Section: Resultsmentioning

confidence: 99%

Use of hyaluronic acid for regeneration of maxillofacial bones

D'Albis¹,

D'Albis

Palma

et al. 2022

Genesis

View full text Add to dashboard Cite

Summary Hyaluronic acid (HA) has been widely used in medicine and is currently of particular interest to maxillofacial surgeons. Several applications have been introduced, including those in which HA is used as a scaffold for bone regeneration, either alone or in combination with other grafting materials, to enhance bone growth. This review aims to analyze the available literature on the use of HA for maxillofacial bone regenerative procedures including socket preservation, sinus augmentation, and ridge augmentation. Medline and PubMed databases were searched for relevant reports published between January 2000 and April 2021. Nine publications describing the use of HA to augment bone volume were identified. Although further studies are needed, these findings are encouraging as they suggest that HA could be used effectively used, in combination with graft materials, in maxillofacial bone regenerative procedures. HA facilitates manipulation of bone grafts, improves handling characteristics and promotes osteoblast activity that stimulates bone regeneration and repair.

show abstract

Section: Resultsmentioning

confidence: 99%

Use of hyaluronic acid for regeneration of maxillofacial bones

D'Albis¹,

D'Albis

Palma

et al. 2022

Genesis

View full text Add to dashboard Cite

show abstract

“…10 It should be noted that HA combined with a demineralized bone matrix was used in the present research because there are studies that indicate that HA only promotes the formation of new bone but does not contribute significantly to bone regeneration, 13 and that if HA is combined with other biomaterials there is positively an improvement in bone defects. 15 In the research carried out by Taz et al, 16 they studied the efficacy of the injectable granule of biphasic calcium phosphate (BCP) supplemented with hyaluronic acid (HA) to promote bone regeneration, obtaining as a result an improvement in bone formation after 4 weeks of implantation and better handling characteristics for BCP-HA than for BCP.…”

Section: Discussionmentioning

confidence: 99%

Regenerating effect of hyaluronic acid on circumferential bone defects in Wistar albino rats.

Bueno-Beltrán¹,

Budiel-Salguero²,

Palacios-Bustamante³

et al. 2021

J Oral Res

View full text Add to dashboard Cite

Objective: To determine the regenerating effect of hyaluronic acid on circumferential bone defects in albino Wistar rats. Material and Methods: An experimental type study was designed and carried out with 15 albino male Wistar rats, 4 months old and weighing between 250 and 350 grams. Two circumferential bone defects 3mm in diameter and 0.8mm deep were created in the calvaria of the parietal bone (on both sides of the midline). One defect was filled with a demineralized bone matrix (control group); while the other defect was filled with the combination of a demineralized bone matrix plus hyaluronic acid (experimental group). Five experimental rats were euthanized at 30, 60 and 90 days after surgery and they were histologically evaluated following the parameters proposed by Heiple. Results: The experimental group presented a better degree of bone regeneration at 30 and 60 postoperative days. Conclusion: Hyaluronic acid is effective in bone regeneration of circumferential bone defects.

show abstract

“…Multichannel granules consisting of BCP are fabricated by a multipass extrusion method and subsequently suspended in a hyaluronic acid solution to yield an injectable material with improved biological properties. In vitro assays using MC3T3-E1 cells and an in vivo rabbit femoral condyle defect model proved the exceeding properties of the hybrid material regarding cell viability and proliferation as well as bone tissue growth together with the upregulation of osteogenic gene and protein expression [139].…”

Section: Calcium Phosphate Hybridsmentioning

confidence: 96%

Polysaccharide-Based Systems for Targeted Stem Cell Differentiation and Bone Regeneration

et al. 2019

View full text Add to dashboard Cite

Bone tissue engineering is an ever-changing, rapidly evolving, and highly interdisciplinary field of study, where scientists try to mimic natural bone structure as closely as possible in order to facilitate bone healing. New insights from cell biology, specifically from mesenchymal stem cell differentiation and signaling, lead to new approaches in bone regeneration. Novel scaffold and drug release materials based on polysaccharides gain increasing attention due to their wide availability and good biocompatibility to be used as hydrogels and/or hybrid components for drug release and tissue engineering. This article reviews the current state of the art, recent developments, and future perspectives in polysaccharide-based systems used for bone regeneration.

show abstract

Bone regeneration of multichannel biphasic calcium phosphate granules supplemented with hyaluronic acid

Cited by 28 publications

References 37 publications

Use of hyaluronic acid for regeneration of maxillofacial bones

Use of hyaluronic acid for regeneration of maxillofacial bones

Regenerating effect of hyaluronic acid on circumferential bone defects in Wistar albino rats.

Polysaccharide-Based Systems for Targeted Stem Cell Differentiation and Bone Regeneration

Contact Info

Product

Resources

About