Summary Hyaluronic acid (HA) has been widely used in medicine and is currently of particular interest to maxillofacial surgeons. Several applications have been introduced, including those in which HA is used as a scaffold for bone regeneration, either alone or in combination with other grafting materials, to enhance bone growth. This review aims to analyze the available literature on the use of HA for maxillofacial bone regenerative procedures including socket preservation, sinus augmentation, and ridge augmentation. Medline and PubMed databases were searched for relevant reports published between January 2000 and April 2021. Nine publications describing the use of HA to augment bone volume were identified. Although further studies are needed, these findings are encouraging as they suggest that HA could be used effectively used, in combination with graft materials, in maxillofacial bone regenerative procedures. HA facilitates manipulation of bone grafts, improves handling characteristics and promotes osteoblast activity that stimulates bone regeneration and repair.
Purpose: Hyaluronic acid (HA) has been used widely in medicine and is currently of particular interest to maxillofacial surgeons. Several applications have been introduced, including those in which HA is used as a scaffold for bone regeneration both alone and in combination with other grafting materials to enhance bone growth. This review aims to analyze the available literature on the use of HA for maxillofacial bone augmentation for prosthetic-driven implant placement procedures. This article also aims to review the specific advantages, applications, and graft materials associated with HA use. Materials and Methods: Medline and PubMed databases were searched for relevant reports published between January 2000 and December 2021. Results and Discussion: Nine publications describing the use of HA to augment bone volume were identified. Administration of HA facilitates surgical manipulation of the graft and promotes osteoblast activity that stimulates bone regeneration and repair. Conclusion: Although further studies are needed, these findings are encouraging, as they suggest that HA might be used effectively together with additional graft materials in maxillofacial bone augmentation procedures.
Background. Implant-supported cantilever prostheses enable a more straightforward rehabilitation and may be a therapeutic option to reduce treatment morbidity, costs, and time. This study evaluated the clinical outcomes of fixed implant-supported partial dentures made of monolithic zirconia with a cantilever design to replace missing posterior teeth. Methods. Fifteen partially edentulous patients received 34 implants and were provided with 16 zirconia fixed partial prostheses (FPPs) with one cantilever extension replacing mandibular or maxillary missing posterior and lateral teeth. Patients were re-examined for up to 4 years. Patient ages ranged from 41 to 65 years, with a mean age of 53±12 years; 47% were female, and 53% were male. The patients were observed for a mean period of 42±6 months with a minimum of 3 years and a maximum of 4 years. Results. Peri-implantitis was observed in two cases. No chipping or fracture of any FPP was detected. Loosening of the abutment screw was a technical complication in one case. The rehabilitation survival rate was 100%. Implant-supported zirconia FPP with one mesial cantilever extension provides an aesthetic, functional treatment alternative to replace missing molars, premolars, and canines. These excellent clinical outcomes occurred over a mean observation time of 42±6 months. Conclusion. Using monolithic zirconia milled with CAD-CAM technology might be an alternative to the metal-ceramic restoration in implant-supported FPP with one cantilever.
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