Bone morphogenetic protein‐mediated type II collagen expression in pilomatricoma and cutaneous mixed tumor

Mieno, Hideki; Kuroda, Kensuke; Tajima, S.

doi:10.1111/j.0303-6987.2005.00289.x

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Cited by 4 publications

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“…In the dermatologic field, there are a few studies about pathogenesis of calcification in pilomatricoma. These studies provide evidence that BMP‐2 expression of shadow cells plays a role of calcification in pilomatricoma 5,6 …”

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confidence: 69%

“…These studies provide evidence that BMP-2 expression of shadow cells plays a role of calcification in pilomatricoma. 5,6 BMPs are multifunctional growth factors that belong to the transforming growth factor b (TGF-b) superfamily. The BMPs are known for roles as instructive signals during embryogenesis and regulation of bone and other tissues like skin in the adult.…”

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confidence: 99%

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The expression of molecular mediators in the idiopathic cutaneous calcification and ossification

et al. 2008

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Our data suggest that BMP-4, beta-catenin, osteopontin, osteonectin and osteocalcin may be involved in the idiopathic cutaneous calcification and ossification. And smooth muscle actin positive mesenchymal cells may be involved in the cutaneous ossification. This study suggests that the idiopathic cutaneous calcification and ossification is highly complicated and regulated active process like ectopic calcification of other tissues.

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confidence: 69%

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confidence: 99%